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Table 6 Subgroup analysis of patients with ischemic and non-ischemic heart disease

From: Regional contributions to left ventricular stroke volume determined by cardiac magnetic resonance imaging in cardiac resynchronization therapy

 

Ischemic heart disease (n = 32)

Non-ischemic heart disease (n = 33)

P

Women

6 (19)

13 (39)

0.07

Age (years)

71 ± 8

63 ± 8

< 0.001

BSA (m2)

1.97 ± 0.19

2.03 ± 0.24

0.26

Diabetes

4 (13)

5 (15)

1.0

QRS-duration (ms)

167 ± 20

167 ± 13

0.96

LBBB

26 (81)

30 (91)

0.30

Heart rate (beats/min)

68 ± 15

67 ± 10

0.87

NIBP (mmHg)

 Systolic

128 ± 18

127 ± 16

0.75

 Diastolic

75 ± 8

77 ± 9

0.47

Medication

 ACEI/ARB

32 (100)

33 (100)

1.0

 Betablocker

28 (88)

30 (91)

0.66

 Diuretics

27 (84)

29 (88)

0.68

Antihyper-lipidemics

29 (91)

12 (36)

 

 Platelet aggregation inhibitors

24 (75)

11 (33)

0.001

NYHA Class

  

0.32

 NYHA Class II

8 (25)

12 (36)

 

 NYHA Class III

23 (72)

18 (55)

 

 NYHA Class IV

1 (3)

3 (9)

 

Echocardiagraphy

 ΔLVESV (%)

− 14 ± 20

− 23 ± 24

0.12

CMR

 EDV (ml)

323 ± 68

329 ± 148

0.82

 ESV (ml)

242 ± 61

250 ± 143

0.77

 SV (ml)

80 ± 26

79 ± 21

0.80

 EF (%)

25 ± 7

27 ± 9

0.40

 CO (l/min)

5.3 ± 1.6

5.3 ± 1.5

0.90

LVAVPD (mm)

7.7 ± 3.0

8.9 ± 3.2

0.15

SVlong%

49 ± 17

57 ± 19

0.10

SVlat%

45 ± 18

37 ± 13

0.07

SVsept%

− 1 ± 14

2 ± 16

0.41

LGE positive

28 (88%)

12 (36%)

< 0.01

  1. Values are expressed as means ± SD or in absolute number and proportion in parenthesis. ΔLVESV, change in left ventricular end-systolic volume from pre to 6 months post CRT echocardiography
  2. ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; BSA, body surface area; CO, cardiac output; CMR, cardiac magnetic resonance imaging, EDV, end-diastolic volume; EF, ejection fraction; ESV, end-systolic volume; LBBB, left bundle branch block; LVAVPD, left ventricular atrioventricular plane displacement; NIBP, non-invasive systemic blood pressure; NYHA, New York Heart Association; SV, stroke volume; SVlong%, longitudinal contribution to SV; SVlat%, lateral contribution to stroke volume; SVsept%, septal contribution to stroke volume