Table 3 Baseline characteristics according to CC7 (mg/mL) quartiles (Q) in the Norwegian population (RACS)
Characteristics | Total n = 847 | Q1 n = 211 | Q2 n = 212 | Q3 n = 213 | Q4 n = 211 | p value |
|---|---|---|---|---|---|---|
CC7 (mg/mL) | 145.2 (114.0–187.7) | 99.5 (87.7–106.3) | 129.1 (123.6–138.5) | 163.8 (152.7–174.8) | 221.2 (203.4–270.9) | < 0.001 |
Age, years | 72.6 (59.0–81.1) | 63.1 (50.1–73.5) | 69.8 (57.4–79.1) | 73.7 (61.7–81.0) | 79.5 (71.6–85.5) | < 0.001 |
Male sex | 519 (61.3) | 140 (66.4) | 129 (60.9) | 128 (60.1) | 122 (57.8) | 0.32 |
Risk markers at baseline | ||||||
hsCRP mg/L | 4.0 (1.7–13.5) | 2.6 (1.2–5.8) | 3.5 (1.7–11.3) | 4.0 (1.7–14.5) | 8.1 (3.0–20.0) | < 0.001 |
BNP pg/mL | 98 (34–310) | 49 (16–164) | 79 (29–189) | 99 (37–334) | 247 (94.0–605.0) | < 0.001 |
eGFR ml/min/1.73m2 | 63 (49–75) | 70 (57–81) | 65 (55–76) | 63 (48–77) | 53 (38–67) | < 0.001 |
Total cholesterol (mmol/L) | 5.2 (4.3–6.0) | 5.3 (4.4–6.2) | 5.4 (4.5–6.1) | 5.1 (4.2–5.9) | 4.8 (4.1–5.8) | 0.009 |
Acute myocardial infarction* | 366 (43.2) | 79 (37.4) | 104 (49.1) | 94 (44.1) | 89 (42.2) | 0.11 |
TnT release (> 10 ng/L) | 456 (53.8) | 91 (43.1) | 117 (55.2) | 114 (53.5) | 134 (63.5) | < 0.001 |
Risk factors | ||||||
Smoking | < 0.001 | |||||
Current smoking | 219 (25.9) | 82 (38.9) | 55 (25.9) | 49 (23.0) | 33 (15.6) | |
Past smoking | 311 (36.7) | 68 (32.2) | 79 (37.3) | 77 (36.2) | 87 (41.2) | |
Hypertension | 356 (42.0) | 60 (28.4) | 93 (43.9) | 99 (46.5) | 104 (49.3) | < 0.001 |
Diabetes mellitus type I | 8 (0.94) | 1 (0.47) | 3 (1.4) | 3 (1.4) | 1 (0.47) | 0.57 |
Diabetes mellitus type II | 108 (12.8) | 16 (7.6) | 24 (11.3) | 25 (11.7) | 43 (20.4) | < 0.001 |
Total cholesterol > 6.5 mmol/L | 131 (15.5) | 38 (18.0) | 30 (14.2) | 35 (16.4) | 28 (13.3) | 0.52 |
BMI (kg/m2) | 25.3 (22.9–28.0) | 25.7 (23.6–28.4) | 25.5 (23.2–27.8) | 25.0 (22.8–27.5) | 24.9 (21.8–27.8) | 0.057 |
History of heart disease | ||||||
Angina pectoris | 374 (44.2) | 77 (36.5) | 88 (41.5) | 96 (45.1) | 113 (53.5) | 0.004 |
Myocardial infarction | 280 (33.1) | 49 (23.2) | 70 (33.0) | 69 (32.4) | 92 (43.6) | < 0.001 |
Previous CABG | 87 (10.3) | 20 (9.5) | 18 (8.5) | 25 (11.7) | 24 (11.4) | 0.65 |
Previous PCI | 87 (10.3) | 22 (10.4) | 20 (9.4) | 25 (11.7) | 20 (9.5) | 0.85 |
Heart failure | 227 (26.8) | 26 (12.3) | 39 (18.4) | 53 (24.9) | 109 (51.7) | < 0.001 |
Treatment prior to admission | ||||||
ACEI/ARB | 288 (34.0) | 44 (20.9) | 60 (28.3) | 79 (37.1) | 105 (49.8) | < 0.001 |
Beta-blocker | 304 (35.9) | 61 (28.9) | 80 (37.7) | 74 (34.7) | 89 (42.2) | 0.036 |
Statins | 293 (34.6) | 66 (31.3) | 65 (30.7) | 85 (39.9) | 77 (36.5) | 0.14 |