Combined effect of hyperhomocysteinemia and smoking on the severity of coronary artery disease in young adults ≤ 35 years of age: a hospital-based observational study

Table 3 Univariate liner regression analysis of the severity of CAD with variables

Variables	β	95% Cl	P
Age	− 0.406	− 1.097, 0.284	0.249
Male	6.102	− 4.304 to 16.509	0.250
BMI	0.002	− 0.436 to 0.440	0.993
Drinker	− 6.805	− 11.952 to − 1.657	0.01
Smoker	9.575	5.321–13.829	< 0.001
Hypertension	0.878	− 3.126 to 4.881	0.667
Diabetes mellitus	3.696	− 1.369 to 8.762	0.152
Hypertriglyceridemia	4.686	0.659–8.713	0.023
Hypercholesterolemia	4.127	− 0.091 to 8.346	0.055
High LDL-C	8.185	3.890–12.481	< 0.001
Low HDL-C	4.304	0.005–8.603	0.049
Family history of CAD	0.294	− 5.698 to 1.973	0.206
Hyperhomocysteinemia	11.463	7.496–15.429	< 0.001
Uric acid	0.026	0.006–0.047	0.013
BUN	0.025	− 0.056 to 0.107	0.543
CR	0.057	− 0.012 to 0.125	0.105

Bold values indicate statistical significance
CAD coronary artery disease, BMI body mass index, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, BUN blood urea nitrogen, CR creatinine, CI confidence interval

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