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Table 2 Clinical diagnosis, angiographic findings, medical treatment and cardiac function of study population

From: Combined effect of hyperhomocysteinemia and smoking on the severity of coronary artery disease in young adults ≤ 35 years of age: a hospital-based observational study

Characteristics

Total (n = 989)

HHcy−Smoker− (n = 153)

HHcy+Smoker− (n = 160)

HHcy−Smoker+ (n = 289)

HHcy+Smoker+ (n = 387)

Diagnosis

     

SCAD

102 (10.31)

32 (20.92)

13 (8.13)a

33 (11.42)a

24 (6.20)a

UAP

379 (38.32)

74 (48.37)

67 (41.88)

97 (33.56)a

141 (36.43)

AMI

508 (51.37)

47 (30.72)

80 (50.00)a

159 (55.02)a

222 (57.36)a

Angiographic findings of vessel involvement

     

None

48 (4.85)

17 (11.11)

11 (6.88)

16 (5.54)

4 (1.03)abc

Single vessel

447 (45.20)

66 (43.14)

70 (43.75)

134 (46.37)

177 (45.74)

Double vessel

236 (23.86)

40 (26.14)

37 (23.13)

60 (20.76)

99 (25.58)

Triple vessel

258 (26.09)

30 (19.61)

42 (26.25)

79 (27.33)

107 (27.65)

Multi-vessel

494 (49.95)

70 (45.75)

79 (49.38)

139 (48.1)

206 (53.23)

Treatment

     

Drug

211 (21.33)

51 (33.33)

33 (20.63)a

54 (18.69)a

73 (18.86)a

Intervention

754 (76.24)

100 (65.36)

124 (77.50)a

228 (78.89)a

302 (78.04)a

Coronary artery bypass grafting

24 (2.43)

2 (1.31)

3 (1.87)

7 (2.42)

12 (3.10)

Cardiac function

     

LVEF

60 (55–66)

62 (58–67)

61 (53–66)

61 (55–66)

60 (53–65)ac

Gensini Score

34 (20–62)

24 (11–43)

32 (13–57.5)a

32 (18.5–50)a

44 (24–78)abc

  1. Data are expressed as the number (%)
  2. SCAD stable coronary artery disease, UAP unstable angina pectoris, AMI acute myocardial infraction, HHcy hyperhomocysteinemia, LVEF left ventricular ejection fraction
  3. ap < 0.05 versus HHcy−Smoker−
  4. bp < 0.05 versus HHcy+Smoker−
  5. cp < 0.05 versus HHcy−Smoker +