Table 1 Study characteristics
References | Year of publication | No. of participants | Men (%) | Age (SD or IQR) | Population | Study design | Reference test | Modalities | Image analysis | Tracers |
|---|---|---|---|---|---|---|---|---|---|---|
Abulizi et al. [44] | 2019 | 27 | 70 | 70 (12) | Known or suspected CA | Prospective | Myocardial histology | PET | Semiquantitative | 18F-NaF |
Aquaro et al. [45] | 2014 | 79 | 61 | 69 (10) | Known CA | Prospective | Myocardial histology electrocardiographic criteria | CMR | Qualitative | NA |
Asif et al. [46] | 2020 | 133 | 53 | 76 (12) | Suspected CA | Retrospective | Myocardial histology | SPECT | Semiquantitative | 99mTc-PYP |
Awaya et al. [47] | 2020 | 10 | 70 | 61 (12) | Suspected CA | Prospective | Myocardial histology | SPECT | Qualitative | 99mTc-aprotinin |
Baggiano et al. [48] | 2020 | 436 | 66 | 67 (13) | Suspected CA | Prospective | Myocardial histology | CMR | Qualitative | NA |
Baroni et al. [49] | 2018 | 21 | 74 | 58 (12) | Suspected CA | Prospective | Myocardial histology | CMR | Qualitative | NA |
Bellevre et al. [50] | 2020 | 30 | 53 | 84 (7) | Suspected CA | Retrospective | Myocardial histology | SPECT | Semiquantitative | 99mTc-HMDP |
Bhatti et al. [51] | 2016 | 126 | 64 | 63 (10) | Suspected CA | Retrospective | Myocardial histology | CMR | Qualitative | NA |
Cappelli et al. [52] | 2019 | 85 | 79 | 77 (9) | Suspected CA | Retrospective | Myocardial histology | SPECT | Semiquantitative | 99mTc-HMDP |
Ezawa et al. [53] | 2018 | 18 | 61 | 51 (15) | Known or suspected CA | Prospective | Myocardial histology | PET | Qualitative | 11C-PIB |
Flaherty et al. [54] | 2020 | 43 | 7 | 77 (9) | Suspected CA | Prospective | Myocardial histology | SPECT | Quantitative | 99mTc-PYP |
Gallini et al. [55] | 2019 | 76 | 80 | 77 (8) | Known or suspected CA | Retrospective | Myocardial histology | SPECT | Semiquantitative | 99mTc-HMDP |
Gillmore et al. [56] | 2016 | 374 | NR | NR | Known or suspected CA | Prospective | Myocardial histology and genetic findings | SPECT | Qualitative | 99mTc-DPD |
Karamitsos et al. [57] | 2013 | 53 | 66 | 62 (11) | Known or suspected CA | Prospective | Myocardial histology | CMR | Qualitative | NA |
Kircher et al. [58] | 2019 | 21 | 64 | 65 (14) | Suspected CA | Prospective | Myocardial histology | CMR | Qualitative | NA |
Lee et al. [59] | 2015 | 19 | 46 | 65 (10) | Suspected CA | Prospective | Myocardial histology | CMR | Qualitative | NA |
Malka et al. [38] | 2020 | 308 | 75 | 73 (8) | Known CA and controls | Retrospective | Myocardial histology | SPECT | Semiquantitative | 99mTc-HMDP |
Martineau et al. [60] | 2019 | 15 | 80 | 69 (11) | CA | Retrospective | Myocardial histology | PET | Qualitative | 18F-NaF |
Masri et al. [61] | 2020 | 233 | 69 | 77 (14) | Suspected CA | Prospective | Diffuse myocardial uptake | SPECT | Semiquantitative | 99mTc-PYP |
Minamimoto et al. [16] | 2020 | 9 | 67 | 64 (14) | Suspected CA | Prospective | Myocardial histology | SPECT | Qualitative | 99mTc-aprotinin |
Moore et al. [62] | 2017 | 21 | 91 | NR | Suspected CA | Prospective | Myocardial histology | SPECT | Semiquantitative | 99mTc-DPD |
Papantoniou et al. [63] | 2015 | 12 | 67 | 69 (12) | Suspected CA | Prospective | Myocardial histology | SPECT | Semiquantitative | 99mTc-PYP |
Papathanasiou et al. [42] | 2020 | 17 | 88 | 71 (9) | Known CA and controls | Retrospective | Myocardial histology | PET | Qualitative | 18F-flutemetamol |
Poterucha et al. [64] | 2020 | 91 | 84 | 72 (9) | Suspected CA | Retrospective | Myocardial histology | SPECT | Qualitative | 99mTc-PYP |
Rapezzi et al. [65] | 2011 | 63 | 62 | 53 (41–66) | Known or suspected CA | Prospective | Myocardial histology | SPECT | Qualitative | 99mTc-DPD |
Régis et al. [66] | 2020 | 40 | 73 | 75 (10) | Suspected CA | Retrospective | H/CL ratio | SPECT | Qualitative | 99mTc-PYP |
Rosengren et al. [41] | 2020 | 51 | 73 | 69 (13) | Known and suspected CA | Prospective | Myocardial histology | PET | Qualitative | 11C-PIB |
Sperry et al. [37] | 2020 | 100 | 75 | 77 (72–82) | Suspected CA | Retrospective | Semiquantitative grade and H/CL ratio | SPECT | Semiquantitative | 99mTc-PYP |
White et al. [67] | 2014 | 25 | 58 | 62 (13) | Suspected CA | Prospective | Myocardial histology | CMR | Semiquantitative | NA |
Wollenweber et al. [39] | 2020 | 32 | 722 | 73 (11) | Suspected CA | Prospective | Myocardial histology | SPECT | Qualitative | 99mTc-DPD |
Zhang et al. [40] | 2020 | 17 | 94 | 77 (8) | Known and suspected CA | Prospective | Myocardial histology | PET | Qualitative | 18F-NaF |