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Table.3 All-cause and CVD mortality according to MetS, general and abdominal obesity phenotypes: Hazard ratios (HR) and 95% confidence intervals (CI) from Cox proportional hazards models of 6517 women in the SAMINOR 1 Survey (2003–2004)

From: Obesity measures, metabolic health and their association with 15-year all-cause and cardiovascular mortality in the SAMINOR 1 Survey: a population-based cohort study

    

Model 1

Model 2

Model 3

 

Cases

Person-years

IR

HR

95% CI

HR

95% CI

HR

95% CI

Outcome: All-cause mortality

Metabolic syndrome

No

343

68,588.7

5.0

Ref

 

Ref

 

Ref

 

Yes

253

28,604.7

8.8

1.14

0.97–1.35

1.15

0.97–1.35

1.11

0.94–1.31

General obesity phenotypes

Metabolically healthy non-obese

154

46,629.4

3.3

Ref

 

Ref

 

Ref

 

Metabolically unhealthy non-obese

230

24,487.6

9.4

1.13

0.92–1.40

1.14

0.92–1.41

1.11

0.90–1.38

Metabolically healthy obese

25

7753.5

3.2

0.64

0.42–0.97

0.68

0.44–1.04

0.63

0.41–0.97

Metabolically unhealthy obese

187

18,322.8

10.2

1.17

0.94–1.46

1.27

1.02–1.59

1.17

0.93–1.47

Abdominal obesity phenotypes

Metabolically healthy non-abdominally obese

119

39,259.1

3.0

Ref

 

Ref

 

Ref

 

Metabolically unhealthy non-abdominally obese

170

20,308.6

8.4

1.12

0.88–1.43

1.14

0.89–1.45

1.12

0.88–1.43

Metabolically healthy abdominally obese

42

12,571.2

3.3

0.71

0.50–1.01

0.75

0.53–1.07

0.71

0.50–1.02

Metabolically unhealthy abdominally obese

265

25,054.5

10.6

1.23

0.99–1.55

1.31

1.04–1.64

1.22

0.97–1.54

Outcome: CVD mortality

Metabolic syndrome

No

73

68,588.7

1.1

Ref

 

Ref

 

Ref

 

Yes

79

28,604.7

2.8

1.55

1.12–2.13

1.53

1.11–2.11

1.46

1.06–2.02

General obesity phenotypes

Metabolically healthy non-obese

16

46,629.4

0.3

Ref

 

Ref

 

Ref

 

Metabolically unhealthy non-obese

73

24,487.6

3.0

2.86

1.65–4.95

2.88

1.66–4.99

2.77

1.59–4.80

Metabolically healthy obese

5

7753.5

0.6

1.08

0.40–2.96

1.12

0.41–3.07

1.05

0.38–2.88

Metabolically unhealthy obese

58

18,322.8

3.2

2.81

1.60–4.94

2.93

1.66–5.15

2.65

1.49–4.72

Abdominal obesity phenotypes

Metabolically healthy non-abdominally obese

16

39,259.1

0.4

Ref

 

Ref

 

Ref

 

Metabolically unhealthy non-abdominally obese

48

20,308.6

2.4

1.90

1.07–3.38

1.93

1.09–3.43

1.86

1.05–3.32

Metabolically healthy abdominally obese

5

12,571.2

0.4

0.55

0.20–1.50

0.57

0.21–1.56

0.54

0.20–1.47

Metabolically unhealthy abdominally obese

83

25,054.5

3.3

2.25

1.30–3.88

2.31

1.34–3.99

2.11

1.21–3.69

  1. Model 1 is the crude model (all models inherently adjusted for age by using attained age as the time-scale). Model 2 was additionally adjusted for smoking, and model 3 was additionally adjusted for leisure-time physical activity, education and alcohol consumption (model 3). We applied stratified Cox models with separate baseline hazards for subgroups of smoking status to satisfy the proportional hazard assumption in all-cause mortality models
  2. IR = crude incidence rate per 1000 person-years, HR = hazard ratio, CI = confidence interval