Fig. 6
From: Structural heart defects associated with ETB mutation, a cause of Hirschsprung disease
Cardiac shrinkage in sl/sl rat was relatively uniform across four major constituents. No significant difference was detected in cardiac constituent/whole heart ratios between sl/sl and the control group. Both shared similar organ/whole heart ratios: LV (0.51 vs. 0.52, p value = 0.72), RV (0.38 vs. 0.40, p value = 0.50), LA (0.042 vs. 0.043, p value = 0.95), and RA (0.079 vs. 0.079, p value = 0.95). This reflects ETB effect was overall uniform across all heart structures, albeit minor regional-dependent impact might be present in RV