Fig. 4
From: Structural heart defects associated with ETB mutation, a cause of Hirschsprung disease
sl/sl rat has lower cardiac growth rates than the control group. Markedly lower cardiac growth rate was detected in sl/sl rat with respect to the control animal, 0.48 mm3/h versus 0.59 mm3/h, p value = 0.05. Similar difference was observed between the two groups in LV (0.24mm3/h vs. 0.31mm3/h, p value = 0.02) and RV (0.18mm3/h vs. 0.23mm3/h, p value = 0.03). Albeit not reaching statistical power, decreasing trend was also seen in LA (0.020mm3/h vs. 0.026mm3/h, p value = 0.18) and RA (0.038mm3/h vs. 0.046mm3/h, p value = 0.10). Aortic arch measurement showed little difference between the two groups: 0.015mm3/h versus 0.017mm3/h, p value = 0.51. RA = Right Atrium; RV = Right Ventricle; LA = Left Atrium; LV = Left Ventricle. *: statistically significant, p value ≤ 0.05