Fig. 3
From: Structural heart defects associated with ETB mutation, a cause of Hirschsprung disease
sl/sl rat has significantly smaller cardiac structures. sl/sl rat has a smaller heart when comparing to the control animals, 39.81mm3 versus 55.22mm3, p value = 0.02. Analyses on heart constituents showed similar trend: LV (20.30mm3 vs. 28.67mm3, p value = 0.01), RV (15.04mm3 vs. 21.98mm3, p value = 0.02), LA (1.66mm3 vs. 2.40mm3, p value = 0.06), and RA (3.11mm3 vs. 4.33mm3, p value = 0.02). Minor volumetric difference in aortic arch was also detected between sl/sl and the control group: 1.29 mm3 versus 1.56mm3, p value = 0.25. RA = Right Atrium; RV = Right Ventricle; LA = Left Atrium; LV = Left Ventricle. *: statistically significant, p value ≤ 0.05