Fig. 2
From: Structural heart defects associated with ETB mutation, a cause of Hirschsprung disease
Grossly normal cardiac morphology and constituents in sl/sl rat. A (4× H&E microscopy), B and C (ex vivo micro-CT, 10.7 µm/voxel) were cardiac illustrations sl/sl rats in coronal views. No detectable gross abnormality was identified. Both image types showed patent cardiac outflow tract with fully formed atria and ventricles. Septal defects were not detected. Major structures were as labelled. Aor = Aorta; RAu = Right Auricle; RA = Right Atrium; RV = Right Ventricle; RVW = Right Ventricular Wall; IVS = Interventricular Septum; LA = Left Atrium; LV = Left Ventricle; LVW = Left Ventricular Wall; Pm = Papillary Muscle; Pul V = Pulmonary Vessel; Asv = Aortic semilunar valve