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Table 1 General and laboratory characteristics and drug history of the study population according to PLR quartiles

From: The association between platelet-to-lymphocyte ratio with mortality among patients suffering from acute decompensated heart failure

Variables

Total

PLR quartiles

P

(n = 405)

Q1

(PLR ≤ 118)

(n = 100)

Q2

(119 < PLR < 198)

(n = 103)

Q3

(198 ≤ PLR < 268)

(n = 101)

Q4

(PLR ≥ 268)

(n = 101)

Age(years)

65.9 ± 13.49

65.3 ± 13.15

66.5 ± 12.8

65.7 ± 12.91

66.25 ± 15.13

0.913

Males (%)

274 (67.7)

72 (72)

68 (66)

64 (63.4)

70 (69.3)

0.580

BMI(kg/m2)

26.85 ± 6.2

26.45 ± 6.9

27.49 ± 7.2

27.32 ± 6

26.32 ± 3.9

0.417

Heart rate (beats per minute)

85.28 ± 19.5

83.64 ± 20.3

86.81 ± 19.2

85.22 ± 18.7

85.41 ± 19.8

0.722

Ischemic heart disease (%)

358 (88.4)

89 (89)

90 (87.4)

89 (88.1)

90 (89.1)

0.978

Diabetes mellitus (%)

170 (42)

42 (42)

38 (36.9)

50 (49.5)

40 (39.6)

0.299

Hypertension (%)

194 (47.9)

47 (47)

51 (49.5)

50 (49.5)

46 (45.5)

0.926

Stroke (%)

18 (4.4)

4 (4)

5 (4.9)

4 (4)

5 (5)

0.977

Kidney diseases (%)

179 (44.2)

44 (44)

47 (45.6)

46 (45.5)

42 (41.6)

0.932

COPD (%)

142 (35.1)

41 (41)d

35 (34)

45 (44.6)

21 (20.8)

0.002

Smoking status (%)

152 (37.5)

38 (38)

36 (35)

37 (36.6)

41 (40.6)

0.864

Systolic blood pressure (mmHg)

121.01 ± 26.9

122.79 ± 26.9

121.01 ± 23.8

119.58 ± 24.2

120.68 ± 25.5

0.839

Diastolic blood pressure (mmHg)

75.67 ± 15.68

76.26 ± 16.6

75.54 ± 15.2

75.76 ± 14.1

75.14 ± 16.8

0.967

Left ventricular ejection fraction (%)

      

 < 30

299 (73.8)

73 (73)

70 (68)

78 (77.2)

78 (77.2)

0.391

 30–40

61 (15.1)

18 (18)

17 (16.5)

12 (11.9)

14 (13.9)

 

 40–50

27 (6.7)

3 (3)

9 (8.7)

9 (8.9)

6 (5.9)

 

 > 50

18 (4.4)

6 (6)

7 (6.8)

2 (2)

3 (3)

 

Hemoglobin (g/dl)

13.59 ± 3

14.27 ± 3b

13.79 ± 2.3

13.08 ± 3.5

13.23 ± 3

0.021

WBC (106/l)

5.4 ± 3.1

8.1 ± 3.7a,b,c

5.8 ± 2.9

4.1 ± 2.1

3.4 ± 0.6

< 0.001

Neutrophils (%)

68 ± 12.3

60.8 ± 14a,b,c

68.4 ± 10.6

66.8 ± 11.1

76 ± 8.1

< 0.001

Lymphocytes (%)

22 ± 9.5

28.1 ± 10.3a,b,c

23 ± 9.2

22 ± 6.9

15.1 ± 6.3

< 0.001

Platelets (109/l)

190.45 ± 68.9

160.23 ± 65.6b,c

175.28 ± 49.4

198.32 ± 59.9

227.97 ± 78.8

< 0.001

Sodium (mEq/l)

136.07 ± 4.8

137.42 ± 7b,c

136.5 ± 2.9

135.6 ± 3.8

134.76 ± 4.4

0.001

Potassium (mEq/l)

3.97 ± 0.5

3.98 ± 0.5

3.93 ± 0.5

3.97 ± 0.5

4.01 ± 0.5

0.762

Blood urea nitrogen (mg/dl)

83.36 ± 52.2

82.61 ± 60.9

84.22 ± 45.8

80.41 ± 48.8

86.2 ± 52.9

0.881

Creatinine (mg/dl)

1.56 ± 1.2

1.42 ± 0.7

1.50 ± 0.5

1.47 ± 0.7

1.84 ± 2.2

0.077

Drug history

      

 Pre-admission

      

  Beta blocker (%)

158 (39)

44 (44)

40 (38.8)

34 (33.7)

40 (39.6)

0.517

  ACEIs/ARBs (%)

200 (49.4)

47 (47)

46 (44.7)

54 (53.5)

53 (52.5)

0.531

  Diuretics (%)

271 (66.9)

62 (62)

72 (69.9)

72 (71.3)

65 (64.4)

0.444

  Statins (%)

205 (50.6)

53 (53)

48 (46.6)

55 (54.5)

49 (48.5)

0.645

  Oral anti-coagulants (%)

108 (26.7)

23 (23)

31 (30.1)

30 (29.7)

24 (23.8)

0.528

 Discharge

      

  Beta blocker (%)

273 (67.4)

67 (67)

72 (69.9)

68 (67.3)

66 (65.3)

0.920

  ACEIs/ARBs (%)

192 (47.4)

49 (49)

50 (48.5)

49 (48.5)

44 (43.6)

0.849

  Diuretics (%)

326 (80.5)

82 (82)

87 (84.5)

78 (77.2)

79 (78.2)

0.532

  Oral anti-coagulants (%)

113 (27.9)

20 (20)

29 (28.2)

37 (36.6)

27 (26.7)

0.072

  1. PLR platelet to lymphocyte ratio, BMI body mass index, COPD chronic obstructive pulmonary disease, ACEI angiotensin-converting enzyme inhibitors, ARB angiotensin receptor blockers, WBC white blood cells
  2. aP < 0.05 compared with quartile 2 resulted from post hoc Bonferroni test
  3. bP < 0.05 compared with quartile 3 resulted from post hoc Bonferroni test
  4. cP < 0.05 compared with quartile 4 resulted from post hoc Bonferroni test
  5. dP < 0.05 compared with quartile 4 resulted from post hoc test with Bonferroni correction