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Table 3 Changes from baseline to 6-month visit in SGLT2 patients

From: Effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors on left ventricular remodelling and longitudinal strain: a prospective observational study

 

Baseline

6-month

Δ from baseline

p

Indexed LVM (g/m2)

98.5 ± 27.9

87.6 ± 18.4

− 10.8 ± 3.3

0.003

LV end-diastolic volume (ml)

103.3 ± 40.0

100.8 ± 34.0

− 2.5 ± 5.0

0.62

LV end-diastolic diameter (mm)

46.9 ± 5.0

45.7 ± 4.3

− 1.2 ± 0.67

0.09

LV ejection fraction (%)

62.9 ± 8.2

62.6 ± 8.4

− 0.4 ± 1.5

0.81

RWT

0.47 ± 0.07

0.46 ± 0.06

− 0.01 ± 0.01

0.44

GLS

− 17.8 ± 2.9

− 19.1 ± 3.1

1.29 ± 0.47

0.01

LA indexed volume (ml/m2)

31.9 ± 9.8

31.2 ± 9.9

− 0.75 ± 1.28

0.56

E/A ratio

0.81 ± 0.39

0.92 ± 0.52

0.10 ± 0.05

0.07

Lateral e’ (cm/s)

8.31 ± 2.19

9.07 ± 2.57

0.76 ± 0.47

0.12

Septal e’ (cm/s)

5.91 ± 1.37

6.57 ± 1.60

0.66 ± 0.25

0.01

E/e’ ratio

10.5 ± 3.6

10.0 ± 3.9

− 0.52 ± 0.53

0.34

  1. LVM left ventricular mass, LV left ventricular, RWT relative wall thickness, GLS global longitudinal strain, LA left atrial