Baseline (n = 19) | 12 months (n = 19) | p value | Controls (n = 20) | |
---|---|---|---|---|
Right atrium | ||||
Volume (mL/m2) | 30 ± 9* | 23 ± 5 | < 0.005 | 23 ± 6 |
Length (mm) | 57 ± 8 | 56 ± 10 | 0.54 | 53 ± 7 |
Width (mm) | 57 ± 12* | 46 ± 8 | < 0.005 | 48 ± 9 |
Right ventricle | ||||
RVMi (g/m2) | 22 ± 7* | 13 ± 7 | < 0.0001 | 12 ± 3 |
End-diastolic volume (mL) | 233 ± 74* | 164 ± 50 | < 0.0001 | 172 ± 41 |
End-systolic volume (mL) | 168 ± 75* | 94 ± 40 | < 0.0005 | 80 ± 23 |
RVDd1 (mm) | 54 ± 8* | 42 ± 8 | < 0.0001 | 43 ± 5 |
RVDd2 (mm) | 48 ± 8* | 38 ± 6 | < 0.0001 | 37 ± 4 |
RV length (mm) | 86 ± 10 | 78 ± 10 | < 0.0001 | 82 ± 8 |
RV sphericity index | 2.5 ± 0.2* | 2.8 ± 0.5 | < 0.01 | 2.8 ± 0.4 |
Stroke volume (mL) | 65 ± 22* | 71 ± 21* | 0.15 | 92 ± 19 |
TV regurgitant volume (mL) | 11 ± 17 | 4 ± 8 | 0.20 | 4 ± 7 |
Ejection fraction (%) | 30 ± 13* | 44 ± 10* | < 0.001 | 54 ± 20 |
Tricuspid valve | ||||
Annular area sys (cm2) | 12.6 ± 3.5 | 11.0 ± 3.2 | 0.11 | 12.4 ± 2.6 |
Annular area dia (cm2) | 14.5 ± 4.2 | 11.7 ± 3.9* | 0.06 | 13.5 ± 2.8 |
Circumference sys (cm) | 15.0 ± 2.6 | 13.9 ± 2.8 | 0.18 | 15.0 ± 2.1 |
Circumference dia (cm) | 16.7 ± 1.9 | 15.9 ± 3.0 | 0.47 | 16.7 ± 1.9 |
Annular height sys (cm) | 1.3 ± 0.5* | 1.1 ± 0.3 | < 0.01 | 1.0 ± 0.3 |
Annular height dia (cm) | 1.3 ± 0.4 | 1.7 ± 0.7 | 0.16 | 1.5 ± 0.4 |
SL distance sys (cm) | 4.0 ± 0.6 | 3.8 ± 0.6 | 0.08 | 3.7 ± 0.5 |
SL distance dia (cm) | 4.4 ± 0.6 | 4.2 ± 0.7 | 0.24 | 4.1 ± 0.5 |
AP distance sys (cm) | 3.9 ± 0.5 | 3.8 ± 0.7 | 0.42 | 4.1 ± 0.5 |
AP distance dia (cm) | 4.1 ± 0.6 | 3.7 ± 0.8* | 0.08 | 4.2 ± 0.6 |
Leaflet area sys (cm2) | 20.1 ± 5.8 | 16.2 ± 6.4 | < 0.005 | 16.9 ± 3.7 |
Tenting volume sys (cm3) | 4.4 ± 2.6* | 1.6 ± 0.9 | < 0.005 | 1.5 ± 0.8 |
Tenting height sys (mm3) | 11.4 ± 3.9* | 7.0 ± 2.2 | < 0.0005 | 7.0 ± 1.9 |
Coaptation height (mm) | 4.9 ± 1.1* | 5.8 ± 1.7* | 0.17 | 7.2 ± 1.5 |
Pulmonary artery | ||||
Cardiac output (L/min) | 3.9 ± 0.9* | 5.1 ± 1.4 | < 0.005 | 4.9 ± 0.7 |
Cardiac index (L/min/m2) | 2.3 ± 0.4* | 2.8 ± 0.6 | < 0.005 | 2.6 ± 0.4 |
Non-invasive derived RV-PA coupling | ||||
SV (mL) / ESV (mL) | 0.49 ± 0.30* | 0.84 ± 0.31* | p < 0.0001 | 1.19 ± 0.20 |