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Table 3 Hazard ratio (95% CI) of cardiovascular disease across tertiles of PRAL and NEAP: Tehran Lipid and Glucose Study (TLGS)

From: Dietary acid load and risk of cardiovascular disease: a prospective population-based study

 

T1

T2

T3

P trend

 < − 16.7 (n = 789)

− 16.7 to − 2.45 (n = 790)

 > − 2.45 (n = 790)

PRAL (mEq/day)

    

 Crude

1

0.67 (0.39–1.14)

0.65 (0.38–1.11)

0.094

 Model 1

1

0.73 (0.43–1.24)

0.79 (0.46–1.36)

0.346

 Model 2

1

0.75 (0.44–1.28)

0.80 (0.46–1.37)

0.367

 

T1

T2

T3

P trend

 < 30.6 (n = 789)

30.6 to 39.3 (n = 794)

 > 39.3 (n = 786)

NEAP (mEq/day)

    

 Crude

1

0.63 (0.37–1.07)

0.50 (0.32–0.96)

0.032

 Model 1

1

0.72 (0.42–1.21)

0.76 (0.44–1.33)

0.986

 Model 2

1

0.73 (0.43–1.23)

0.76 (0.44–1.32)

0.988

  1. Cox proportional hazard regression model was used to estimate hazard ratio (HR) and 95% confidence intervals (CI) for cardiovascular disease across tertiles of dietary acid load
  2. PRAL, potential renal acid load; NEAP, net endogenous acid production
  3. Model 1: adjusted for sex, age, smoking status
  4. Model 2: adjusted for sex, age, smoking status, dietary energy intake (kcal/d), total fat intake (g/d)