Fig. 7

Antagonistic effect of CS and ABCA1 overexpression on miR-33-5p inhibition. A, B The levels of ABCA1 and CS mRNA and protein expression in response to transfections. C The levels of senescence-associated β-galactosidase (SA-β-gal) activity in VECs. D The percentages of apoptotic VECs. The repeated results were shown in Aditional file 2: Supplementary Figure 5. E The expression of apoptosis-related proteins. Ox-LDL, oxidized low-density lipoprotein. NC, overexpression negative control. The original bands of WB are presented in Additional file 1: [2A and 2B]. **p < 0.01 vs. control by one-way ANOVA followed by Tukey's post hoc test. ^&&p < 0.01 vs. ox-LDL by one-way ANOVA followed by Tukey's post hoc test. ^##p < 0.01 vs. OE-ABCA1 by the one-way ANOVA followed by Tukey's post hoc test. The above experiments were repeated three times and the mean value was obtained