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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: MicroRNA-33-5p inhibits cholesterol efflux in vascular endothelial cells by regulating citrate synthase and ATP-binding cassette transporter A1

Fig. 2

Effect of miR-33-5p inhibition on VECs. A the relative expression profiles of miR-33-5p, HMGCR, ABCA1, and CS mRNA. B The expression of HMGCR, ABCA1, and CS proteins in response to miR-33-5p inhibition. The original bands of WB are presented in Additional file 1: [1B]. C the levels of CS, IL-6, and TNF-α in VECs. D the cellular cholesterol efflux to ApoA 1 (50 μg/well) in VECs. Ox-LDL, oxidized low-density lipoprotein.NC, inhibitor negative control. **p < 0.01 vs. control by one-way ANOVA followed by Tukey's post hoc test. &&p < 0.01 vs. ox-LDL by one-way ANOVA followed by Tukey's post hoc test. The above experiments were repeated three times and the mean value was obtained

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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