Table 2 Overall and subgroup analysis of association between eNOS rs1799983 polymorphism and hypertension under different models
Categories | T versus G | GT versus GG | TT versus GG | GT + TT versus GG | TT versus GG + GT | GT versus GG + TT | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | (95% CI) | I2 (%) | OR | (95%CI) | I2 (%) | OR | (95%CI) | I2 (%) | OR | (95%CI) | I2 (%) | OR | (95%CI) | I2 (%) | OR | (95%CI) | I2 (%) | |
Overall | 1.44 | (1.26,1.63) | 85 | 1.34 | (1.18,1.52) | 75 | 1.80 | (1.41,2.31) | 65 | 1.42 | (1.25,1.63) | 79 | 1.68 | (1.35,2.08) | 58 | 1.24 | (1.11,1.40) | 73 |
Region | ||||||||||||||||||
 China | 1.40 | (1.23,1.59) | 72 | 1.35 | (1.18,1.55) | 65 | 1.54 | (1.24,1.93) | 24 | 1.42 | (1.23,1.63) | 69 | 1.47 | (1.19,1.81) | 24 | 1.29 | (1.12,1.49) | 67 |
 Other | 1.47 | (1.12,1.91) | 92 | 1.31 | (1.01,1.71) | 85 | 2.05 | (1.24,3.40) | 82 | 1.44 | (1.09,1.89) | 87 | 1.89 | (1.24,2.88) | 77 | 1.16 | (0.94,1.44) | 79 |
Ethnicity | ||||||||||||||||||
 Asian | 1.42 | (1.27,1.58) | 69 | 1.37 | (1.21,1.54) | 63 | 1.64 | (1.35,2.00) | 23 | 1.43 | (1.27,1.61) | 66 | 1.56 | (1.29,1.88) | 23 | 1.31 | (1.15,1.48) | 66 |
 Other | 1.44 | (0.98,2.12) | 94 | 1.28 | (0.87,1.87) | 88 | 2.07 | (1.05,4.08) | 88 | 1.42 | (0.94,2.15) | 91 | 1.87 | (1.07,3.25) | 83 | 1.07 | (0.80,1.43) | 83 |