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Table 4 Effect size of sST2/LVMI on the composite outcome in prespecified and exploratory subgroups

From: Increased ratio of sST2/LVMI predicted cardiovascular mortality and heart failure rehospitalization in heart failure with reduced ejection fraction patients: a prospective cohort study

Characteristic

No of participants

Effect size (95% CI)

P value

P for interaction

Age (years)

 < 60

33

1.13 (0.93, 1.38)

0.2213

0.0380

 ≥ 60

12

3.77 (0.93, 15.26)

0.0633

Gender

 Female

9

4.18 (1.08, 16.16)

0.0382

0.0140

 Male

36

1.17 (0.95, 1.45)

0.1446

Systolic blood pressure (mmHg)

 < 140

35

1.20 (0.96, 1.51)

0.1139

0.0466

 ≥ 140

10

3.66 (0.98, 13.65)

0.0529

Serum uric acid (μmol/L)

 < 416

14

2.43 (1.39, 4.25)

0.0018

0.0052

 ≥ 416

31

1.09 (0.83, 1.42)

0.5386

High density lipoprotein cholesterol, mean (SD) (mmol/L)

 < 0.9

22

1.16 (0.86, 1.56)

0.3251

0.0361

 ≥ 0.9

21

2.16 (1.27, 3.67)

0.0042

  1. Above model adjusted for sex; age
  2. In each case, the model is not adjusted for the stratification variable