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Table 1 Comparison of clinical characteristics between patients with and without elevated CK-MB

From: Predictive value of creatine kinase MB for contrast-induced acute kidney injury among myocardial infarction patients

Characteristic

Overall (n = 1131)

log(CK-MB) ≤ 4.70(n = 920)

log(CK-MB) > 4.70

(n = 211)

p-value

Demographic characteristics

Age (years)

60.87 ± 12.05

60.90 ± 12.00

60.71 ± 12.28

0.834

Male gender

932 (82.40%)

761 (82.72%)

171 (81.04%)

0.634

Weight (kg)

65.74 ± 10.84

65.71 ± 10.96

65.89 ± 10.31

0.842

BMI (kg/m2)

23.91 ± 3.21

23.91 ± 3.24

23.93 ± 3.06

0.958

Medical history and clinical condition

CI-AKI

62 (5.48%)

37 (4.02%)

25 (11.85%)

< 0.001

Smoking history

542 (47.92%)

424 (46.09%)

118 (55.92%)

0.012

DM

295 (26.08%)

243 (26.41%)

52 (24.64%)

0.659

Hypertension

562 (49.69%)

471 (51.20%)

91 (43.13%)

0.042

Hyperlipidemia

139 (12.29%)

106 (11.52%)

33 (15.64%)

0.127

CKD

607 (53.67%)

496 (53.91%)

111 (52.61%)

0.790

CHF

460 (40.67%)

368 (40.00%)

92 (43.60%)

0.377

Anterior infarction

399 (35.28%)

291 (31.63%)

108 (51.18%)

< 0.001

Hypotension

86 (7.60%)

59 (6.41%)

27 (12.80%)

0.003

Anemia

321 (28.38%)

275 (29.89%)

46 (21.80%)

0.023

IABP

42 (3.71%)

28 (3.04%)

14 (6.64%)

0.022

LVEF (%)

55.17 ± 11.34

55.91 ± 11.37

52.02 ± 10.69

< 0.001

Procedure

Emergent PCI

976 (86.30%)

782 (85.00%)

194 (91.94%)

0.011

Laboratory examination

GLU(mmol/L)

8.16 ± 3.89

8.03 ± 3.88

8.71 ± 3.91

0.022

Hb(g/L)

128.05 ± 20.46

128.73 ± 20.21

125.05 ± 21.34

0.020

hct

40.62 ± 5.87

40.39 ± 5.89

41.64 ± 5.68

0.006

Scr(mg/dl)

95.37 ± 40.66

96.20 ± 42.43

91.72 ± 31.62

0.148

CCR(ng/ml)

73.70 ± 28.88

73.36 ± 28.86

75.18 ± 28.98

0.410

eGFR(ml/min/1.73mm2)

80.98 ± 26.73

80.69 ± 26.89

82.26 ± 26.04

0.441

BUN(mmol/L)

5.00 [3.90, 6.50]

4.91 [3.90, 6.48]

5.20 [4.03, 6.58]

0.143

HDL-C(mmol/L)

1.00 ± 0.28

0.98 ± 0.27

1.08 ± 0.33

< 0.001

ALB(g/L)

36.10 ± 5.15

36.07 ± 5.12

36.23 ± 5.31

0.712

Treatment during hospitalization

ACEI/ARB

145 (12.82%)

133 (14.46%)

12 (5.69%)

0.001

Beta-blockers

611 (54.02%)

532 (57.83%)

79 (37.44%)

< 0.001

CCB

89 (7.87%)

84 (9.13%)

5 (2.37%)

0.002

Statins

912 (80.64%)

764 (83.04%)

148 (70.14%)

< 0.001

Hypoglycemic drugs

125 (11.05%)

115 (12.50%)

10 (4.74%)

0.002

Diuretic

261 (23.08%)

201 (21.85%)

60 (28.44%)

0.050

Contrast dose(ml)

113.80 ± 50.15

112.14 ± 50.05

121.02 ± 50.08

0.021

  1. CK-MB creatine kinase isoenzymes/creatine kinase-MB, BMI body mass index, CI-AKI contrast-induced acute kidney injury, DM diabetes mellitus, CKD chronic kidney disease, CHF congestive heart failure, IABP intra-aortic ballon pump, LVEF left ventricular ejection fraction, PCI percutaneous coronary intervention, GLU blood glucose, Hb hemoglobin, hct hematocrit, Scr serum creatinine, CCR Creatinine Clearance Rate, eGFR estimated glomerular filtrationrate, BUN blood urea nitrogen, HDL-C high density lipoprotein cholesterol, ALB albumin, ACEI/ARB angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, CCB calcium channel blocker