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Table 1 Characters of the study population with and without valvular heart disease

From: Current status and etiology of valvular heart disease in China: a population-based survey

 

Total (n = 31,499)

VHD (n = 1309)

No VHD (n = 30,190)

P value

Gender

   

0.308

 Male (%)

50.7 (49.0–52.5)

48.2 (42.9–53.5)

50.8 (49.0–52.7)

 

 Female (%)

49.3 (47.5–51.0)

51.8 (46.5–57.1)

49.2 (47.3–51.0)

 

Age (mean, years)

51.8 (51.0–52.5)

61.6 (59.9–63.2)

51.4 (50.7–52.1)

< 0.001

BMI (mean, Kg/m2)

24.7 (24.3–25.0)

24.2 (23.5–24.9)

24.7 (24.3–25.1)

0.058

Region

   

0.134

 East (%)

44.1 (20.1–68.2)

49.2 (15.4–82.9)

43.9 (20.1–67.8)

 

 Central (%)

34.5 (11.0–58.0)

21.7 (7.8–47.8)

35.0 (11.3–58.7)

 

 West (%)

21.4 (8.0–45.9)

29.1 (0.0–61.7)

21.0 (7.9–45.2)

 

Residence

   

0.407

 Rural (%)

37.5 (22.3–52.7)

44.3 (15.1–73.7)

37.2 (22.4–52.0)

 

 Urban (%)

62.5 (47.3–77.7)

55.7 (26.4–84.9)

62.8 (48.0–77.6)

 

Heart diseases history

 Ischemia (%)

0.5 (0.2–1.0)

1.9 (0.8–4.8)

0.4 (0.2–0.9)

< 0.001

 AF (%)

0.7 (0.5–1.1)

4.5 (2.9–6.9)

0.6 (0.4–0.9)

< 0.001

 Systolic HF (%)

0.8 (0.6–1.1)

3.9 (2.6–5.9)

0.7 (0.5–1.0)

< 0.001

 DCM (%)

0.3 (0.2–0.5)

3.5 (1.8–6.7)

0.2 (0.1–0.3)

< 0.001

 HCM (%)

0.2 (0.1–0.4)

0.8 (0.3–2.0)

0.2 (0.1–0.3)

< 0.001

 CHD (%)

0.2 (0.1–0.4)

1.4 (0.6–3.3)

0.1 (0.0–0.3)

< 0.001

Comorbidities

 Hypertension (%)

35.1 (32.8–37.4)

51.9 (48.4–55.4)

34.4 (32.2–36.7)

< 0.001

 Stroke (%)

1.6 (1.0–2.4)

3.3 (1.8–6.1)

1.5 (1.0–2.3)

0.004

 Dyslipidemia (%)

32.4 (28.4–36.4)

28.9 (23.6–34.1)

32.5 (28.5–36.5)

0.015

 Diabetes (%)

8.5 (7.5–9.7)

9.0 (7.5–10.8)

8.5 (7.4–9.8)

0.581

 CKD (%)

4.6 (3.7–5.7)

11.0 (8.4–14.2)

4.3 (3.5–5.3)

< 0.001

Echocardiography measurements

 LAap (mm)

31.2 (30.4–32.1)

34.3 (32.9–35.7)

31.1 (30.3–32.0)

< 0.001

 LVEDD (mm)

46.2 (45.5–47.0)

48.2 (47.2–49.2)

46.2 (45.4–46.9)

< 0.001

 IVSd (mm)

9.6 (9.3–9.8)

10.0 (9.4–10.6)

9.5 (9.2–9.8)

0.077

 LVESD (mm)

30.0 (29.3–30.8)

32.2 (31.1–33.3)

30.0 (29.2–30.7)

< 0.001

 LVEF (%)

64.4 (62.8–65.9)

62.7 (60.7–64.7)

64.4 (62.9–66.0)

< 0.001

  1. Data were represented as means or percentage (95% CI)
  2. All values were weighted to represent the total population of Chinese aged 35 years or older based on the Chinese census 2010
  3. VHD, valvular heart disease; BMI, body mass index; AF, atrial fibrillation; HF, heart failure; DCM, Dilated Cardiomyopathy; HCM, Hypertrophic Cardiomyopathy; CHD, congenital heart disease; CKD, chronic kidney disease. LAap, the anteroposterior diameter of the left atrium; LVEDD, the diameter of the left ventricle at end-diastole; IVSd, the thickness of the interventricular septum; LVESD, the left ventricle end-systolic diameter; LVEF, the left ventricle ejection fraction
  4. P value for t-test (continuous) and x2 or Fisher’s exact test (categorical) to assess the difference between population with VHD and those without it