Table 2 Events during 1 year follow-up for all-cause mortality, composite endpoint and hospitalizations
Endpoint | Calendar period | n (%) events | Event rate per 100 person years (95% CI) | Event rate per 100 person years (95% CI) adjusted for age and sex |
|---|---|---|---|---|
All-cause mortality | 2003–2015 | 881 (11.2%) | 12.0 (11.2–12.8) | 8.9 (8.1–9.7) |
Period 1 | 254 (12.5%) | 13.6 (12.0–15.4) | 10.7 (9.3–12.2) | |
Period 2 | 365 (10.9%) | 11.6 (10.4–12.8) | 8.3 (7.4–9.3) | |
Period 3 | 262 (10.6%) | 11.3 (10.0–12.8) | 8.1 (7.1–9.3) | |
Transplantation | 2003–2015 | 55 (0.7%) | 0.8 (0.6–1.0) | 0.4 (0.3–0.6) |
Period 1 | 10 (0.5%) | 0.5 (0.3–1.0) | 0.3 (0.1–0.5) | |
Period 2 | 30 (0.9%) | 1.0 (0.6–1.4) | 0.5 (0.3–0.8) | |
Period 3 | 15 (0.6%) | 0.6 (0.4–1.1) | 0.4 (0.2–0.6) | |
HF hospitalization | 2003–2015 | 2406 (30.6%) | 40.8 (39.2–42.5) | 40.8 (39.2–42.4) |
Period 1 | 659 (32.5%) | 44.8 (41.5–48.4) | 45.0 (41.7–48.6) | |
Period 2 | 1050 (31.2%) | 41.7 (39.2–44.3) | 41.6 (39.2–44.2) | |
Period 3 | 697 (28.1%) | 36.5 (33.9–39.3) | 36.4 (33.8–39.2) | |
CV hospitalization | 2003–2015 | 3091 (39.3%) | 56.7 (54.7–58.8) | 56.5 (54.5–58.5) |
Period 1 | 831 (41.0%) | 61.4 (57.3–65.7) | 61.8 (57.7–66.2) | |
Period 2 | 1373 (40.8%) | 59.7 (56.5–62.9) | 59.2 (56.1–62.4) | |
Period 3 | 887 (35.8%) | 49.4 (46.2–52.8) | 49.1 (45.9–52.4) | |
Any hospitalization | 2003–2015 | 3540 (45.0%) | 68.3 (66.0–70.5) | 68.0 (65.8–70.3) |
Period 1 | 947 (46.7%) | 73.8 (69.2–78.7) | 74.6 (70.0–79.5) | |
Period 2 | 1580 (47.0%) | 72.6 (69.0–76.2) | 72.0 (68.5–75.6) | |
Period 3 | 1013 (40.8%) | 58.7 (55.1–62.4) | 58.2 (54.7–61.9) | |
Composite endpoint | 2003–2015 | 3810 (48.4%) | 73.5 (71.2–75.8) | 72.9 (70.6–75.3) |
Period 1 | 1024 (50.5%) | 79.8 (75.0–84.9) | 80.6 (75.8–85.7) | |
Period 2 | 1681 (50.0%) | 77.2 (73.5–81.0) | 76.2 (72.6–80.0) | |
Period 3 | 1105 (44.5%) | 64.0 (60.3–67.9) | 63.1 (59.5–66.9) |