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Table 2 Summary of IVIG dose, ultrasound cardiography and optical coherence tomography data in both Group R and Group N

From: Intimal thickening and disruption of the media occur in the arterial walls of coronary arteries not associated with coronary arterial aneurysms in patients with Kawasaki disease

 

Group R (n = 18)

Group N (n = 18)

p value

Total dose of IVIG (mg/kg)

2600* (0–4200)

2500* (0–4000)

p = 0.820

UCG-determined coronary artery diameter Z-score in the acute phase (i.e., time of first CAG)

7.13* (3.65–13.88)

1.81* (-0.18–2.23)

p < 0.001

UCG-determined coronary artery diameter Z-score in the convalescent phase (i.e., time of OCT)

0.64* (-0.02–2.11)

0.48* (-0.67–1.60)

p = 0.311

Difference in UCG-determined coronary artery diameter Z-scores between acute and convalescent phases

6.26* (2.59–13.9)

1.14* (0.22–2.14)

p < 0.001

Maximum intimal thickness (µm)

475* (386–646)

355* (118–552)

p = 0.007

Number of abnormal intimal thickening (> 400 µm), n (%)

17 (94)

7 (39)

p < 0.001

Intimal cross-sectional area (mm2)

4.12* (2.04–7.86)

2.88* (1.45–5.70)

p = 0.029

Disruption of the media, n (%)

18 (100)

12 (67)

p = 0.020

  1. IVIG intravenous immunoglobulin, CA coronary artery, CAG coronary angiography, OCT optical coherence tomography, UCG ultrasound cardiography, KD Kawasaki disease
  2. *Median (minimum–maximum)