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Table 2 Univariate and multivariable Cox hazards analysis of the training cohort

From: A prognostic nomogram for long-term major adverse cardiovascular events in patients with acute coronary syndrome after percutaneous coronary intervention

Variables

Univariate

Multivariate

Score

HR(95% CI)

P value

HR(95% CI)

P value

Statistically significant factors

Age, year

     

  < 65

Ref

Ref

Ref

Ref

0

 65–75

1.636 (1.157–2.314)

0.005

1.295 (0.909–1.847)

0.153

31

  ≥ 75

2.807 (2.015–3.910)

< 0.001

1.866 (1.307–2.663)

0.001

75

LAD stenosis ≥ 50%

2.192 (1.445, 3.327)

< 0.001

1.909 (1.247–2.925)

0.003

78

RCA stenosis ≥ 50%

1.969 (1.444, 2.684)

< 0.001

1.854 (1.350–2.545)

 < 0.001

74

Lactate ≥ 2 mmol/L

1.604 (1.096, 2.347)

0.015

1.555 (1.051–2.299)

0.027

53

BNP, pg/mL

  < 500

Ref

Ref

Ref

Ref

0

 500–1000

1.467 (1.002, 2.150)

0.049

1.105 (0.744–1.642)

0.621

12

  ≥ 1000

3.506 (2.567, 4.789)

< 0.001

2.284 (1.620–3.219)

< 0.001

100

LVEF < 40%

2.138 (1.585, 2.885)

< 0.001

1.607 (1.167–2.211)

0.004

57

Men

0.508 (0.375, 0.689)

< 0.001

   

LCX stenosis ≥ 50%

1.394 (1.051, 1.848)

0.021

   

Hypertension

1.523 (1.137, 2.040)

0.005

   

Diabetes

1.310 (0.952, 1.803)

0.097

   

Atrial fibrillation

1.841 (1.223, 2.771)

0.003

   

Kidney disease

2.284 (1.367, 3.814)

0.002

   

EGFR < 60 mL/min/1.73 m2

2.149 (1.618, 2.855)

< 0.001

   

Creatinine > 186 μmol/L

2.402 (1.566,3.684)

< 0.001

   

Haemoglobin < 120 g/L

1.831 (1.370, 2.448)

< 0.001

   

Statistically non-significant factors

     

Peripheral artery stenosis

1.290 (0.928, 1.793)

0.129

   

Previous stroke

1.419 (0.924, 2.179)

0.109

   

Previous cardiac arrest

1.193 (0.611, 2.331)

0.605

   

Uric acid, μmol/L

1.310 (0.926, 1.854)

0.128

   
  1. BNP brain natriuretic peptide, EGFR estimated glomerular filtration rate, LAD left anterior descending artery, LCX left circumflex artery, LVEF left ventricular ejection fraction, RCA right coronary artery