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Table 3 Comparison of the clinical characteristics between patients with and without AKI (n = 60)

From: Acute kidney injury predicts poor left ventricular function for patients with peripartum cardiomyopathy

Characteristic

AKI (n = 11)

Non-AKI (n = 49)

P value

Age (years)

32 ± 6

30 ± 5

0.356

Primiparous (%)

8 (72.7)

28 (57.1)

0.34

Cesarean section (%)

11 (100.0)

43 (91.8)

1.000

NYHA III–IV (%)

11 (100)

38 (77.6)

0.189

Hospitalization time (days)

14 (8–23)

11 (7–15)

0.105

Hypertension (%)

0

6 (12.2)

0.221

Diabetes mellitus (%)

0

4 (8.2)

1.000

PPCM history (%)

0

3 (6.1)

1.000

Pregnancy-induced hypertension syndrome (%)

0

5 (10.2)

0.573

Preeclampsia (%)

3 (27.3)

4 (8.2)

0.108

SBP (mmHg)

112 ± 20

118 ± 17

0.334

DBP (mmHg)

79 ± 16

76 ± 13

0.52

HR (bpm)

106 ± 19

101 ± 20

0.408

Echocardiographic findings

   

 LVEF (%)

29 ± 11

38 ± 13

0.026

 Left ventricular thrombosis (%)

3 (27.3)

2 (4.1)

0.039

 LVEDD (mm)

52 ± 8

47 ± 9

0.386

Electrocardiographic findings

   

ST-T changes (%)

10 (90.9)

34 (69.4)

0.259

QRS time (ms)

88 ± 10

96 ± 23

0.397

QTc time (ms)

457 ± 54

460 ± 37

0.803

Hemoglobin (g/L)

126 ± 17

122 ± 16

0.485

Platelet (G/L)

238 ± 82

267 ± 84

0.3

ALT (U/L)

26 (13–83)

21 (12–43)

0.233

AST (U/L)

27 (25.3–29.4)

22 (16–31)

0.097

Serum creatinine (μmol/L)

79.5 (63.4–98.3)

55.5 (52.95–65.75)

0.016

BNP (pg/mL)

2243 (1272–5000)

546.55 (104.63–1403.75)

0.001

Ventilator (%)

3 (27.3)

3 (6.1)

0.069

IABP (%)

1 (9.1)

0

0.183

ECMO (%)

1 (9.1)

0

0.183

CRRT (%)

2 (18.2)

0

0.031

Diuretic (%)

11 (100)

49 (100)

1.000

ACEI/ARB (%)

7 (63.6)

33 (67.3)

1.000

β-blockers (%)

6 (54.5)

36 (73.5)

0.216

Ivabradine (%)

0

3 (6.1)

1.000

Anticoagulation (%)

6 (54.5)

5 (10.2)

0.001

Digoxin (%)

10 (90.9)

20 (40.8)

0.006

Vasoactive agents (%)

2 (18.2)

1 (2.0)

0.084

  1. NYHA New York Heart Association, PPCM peripartum cardiomyopathy, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, LVEF left ventricular ejection fraction, LVEDD left ventricular end-diastolic diameter, ALT alanine transaminase, AST aspartate transaminase, AKI acute kidney injury, IABP intra-aortic balloon pump, ECMO extracorporeal membrane oxygenation, CRRT continuous renal replacement therapy, ACEI/ARB angiotensin-converting enzyme inhibitor/angiotensin receptor blocker