Fig. 3

PROMIS GH domain scores, pericardial pain, and c-reactive protein levels over time by participant group. This figure shows the change in the GPH and GMH domain scores over the study period for the A-RP group and the CSD-RP group, and the trend between these HRQoL scores and patient-reported pericardial pain and serum marker of inflammation (CRP). For the A-RP group, pain scores and CRP levels decrease over the study period, while HRQoL scores increase. For the CSD-RP group, pericardial pain and CRP (low at baseline, as expected because these participants entered the trial while not in active flare) remain low over the course of the study even while tapering and discontinuing CS, while HRQoL scores increase over time. BL = baseline; CRP = c-reactive protein; D = day; EoEP = end of extension period; EoTP = end of treatment period; NRS = numeric rating scale; QoL = quality of life; SE = standard error; W = week