Hemodynamic change in patients with hypertrophic obstructive cardiomyopathy before and after alcohol septal ablation using 4D flow magnetic resonance imaging: a retrospective observational study

Table 6 Comparison of hemodynamic parameters in the ascending aorta and intra-LV

	Before ASA n = 11	After ASA n = 11	P
AAO
Vortex	11 (100%)	8 (73%)	0.083
Helix	5 (45%)	4 (36%)	0.564
Vortex + Helix	1.45 ± 0.52	1.09 ± 0.30	0.046
Vortex area, mm²	7317 ± 3964	6000 ± 4265	0.117
Vortex/Helix duration, ms	744 ± 291	467 ± 258	< 0.001
Vortex/Helix phase count, phases	14.8 ± 4.4	10.5 ± 5.8	< 0.001
WSS_outer, Pa	1.15 ± 0.37	1.07 ± 0.56	0.575
WSS_inner, Pa	0.88 ± 0.21	0.87 ± 0.37	0.949
LV
Diastolic anterior vortex area, mm²	1628 ± 420	2974 ± 539	0.009
Diastolic posterior vortex area, mm²	458 (0–978)	380 (0–2076)	0.374
Systolic LVOT vortex	7 (63.6%)	1 (9.1%)	0.014

Data are expressed as mean ± standard deviation or median (interquartile range)
ASA, alcohol septal ablation; AAO, ascending aorta; LV, left ventricle; LVOT, left ventricular outflow tract; WSS_inner, wall shear stress at inner curvature of ascending aorta; WSS_outer, wall shear stress at outer curvature of ascending aorta; CIED, cardiac implantable electrical device; CMR, cardiac magnetic resonance; HOCM, hypertrophic obstructive cardiomyopathy; ICD, implantable cardioverter defibrillator; LVOTO: left ventricular outflow tract obstruction; MRI, magnetic resonance imaging; MVO, mid-ventricular obstruction; WSS, wall shear stress; WSS_inner, wall shear stress at inner curvature of aortic arch; WSS_outer, wall shear stress at outer curvature of aortic arch; PPG, peak pressure gradient

ISSN: 1471-2261