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Fig. 7 | BMC Cardiovascular Disorders

Fig. 7

From: Hsa_circ_0004831 downregulation is partially responsible for atorvastatinalleviated human umbilical vein endothelial cell injuries induced by ox-LDL through targeting the miR-182-5p/CXCL12 axis

Fig. 7

MiR-182-5p inhibition reversed the effect of ATV by increasing the expression of CXCL12 in ox-LDL-treated HUVECs. a The efficiency of CXCL12 interference. 100 mg/L ox-LDL-treated HUVECs with the addition of ATV were transfected with anti-miR-182-5p or anti-miR-182-5p + si-CXCL12#1, with anti-miR-NC or anti-miR-182-5p + si-NC. b, c The expression of CXCL12 mRNA and protein in these cells. d Cell viability in these cells. e, f Cell apoptosis and cell cycle were investigated using flow cytometry assay. g, h The levels of MDA and SOD in these cells. i, j The release of IL-6 and IL-1β in these cells *P < 0.05, **P < 0.01, ***P < 0.001

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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