Fig. 5

Hsa_circ_0004831 overexpression reversed the effect of ATV by targeting miR-182-5p in ox-LDL-treated HUVECs. a The efficiency of miR-182-5p mimic. 100 mg/L ox-LDL-treated HUVECs with the addition of ATV were transfected with circRNA or circRNA + miR-182-5p, with pCD-ciR or miR-NC as the control. b The expression of miR-182-5p in these cells was checked by qPCR. c Cell viability in these cells was checked using CCK-8 assay. d, e Cell apoptosis and cell cycle in these cells were monitored using flow cytometry assay. f, g The levels of MDA and SOD in these cells. h, i The release of IL-6 and IL-1β in these cells. *P < 0.05, **P < 0.01, ***P < 0.001