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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: Hsa_circ_0004831 downregulation is partially responsible for atorvastatinalleviated human umbilical vein endothelial cell injuries induced by ox-LDL through targeting the miR-182-5p/CXCL12 axis

Fig. 2

The expression of hsa_circ_0004831 was promoted in ox-LDL-treated HUVECs but impaired in ox-LDL-treated HUVECs with the addition of ATV. a The treatment of different concentrations of ox-LDL (0, 25, 50, 100 and 200 mg/L) on HUVEC viability. b Cell viability in 100 mg/L ox-LDL-treated HUVECs with the addition of different concentrations of ATV (0, 2.5, 5 and 10 μM). c The expression of hsa_circ_0004831 in ox-LDL-treated HUVECs. d The expression of hsa_circ_0004831 in ox-LDL-treated HUVECs with the addition of ATV. e Schematic diagram revealed the formation of hsa_circ_0004831. f, g The stability of hsa_circ_0004831 was examined by RNase R and actinomycin D. *P < 0.05, **P < 0.01, ***P < 0.001

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