Table 3 The results for KEGG analysis in stable CAD patients compared to healthy subjects
Gene set | Description | Size | Leading edge number | ES | NES | P value | FDR |
|---|---|---|---|---|---|---|---|
hsa04621 | NOD-like receptor signaling pathway | 8 | 6 | − 0.77061 | − 2.0947 | 0.0014245 | 0.0039551 |
hsa04060 | Cytokine-cytokine receptor interaction | 7 | 4 | − 0.77594 | − 1.9948 | 0.001462 | 0.0050427 |
hsa05132 | Salmonella infection | 5 | 4 | − 0.87092 | − 2.0026 | 0 | 0.0051911 |
hsa04657 | IL-17 signaling pathway | 7 | 6 | − 0.8278 | − 2.1093 | 0 | 0.0051911 |
hsa04010 | MAPK signaling pathway | 7 | 6 | − 0.7715 | − 1.9341 | 0.0014451 | 0.006427 |
hsa04151 | PI3K-Akt signaling pathway | 7 | 5 | − 0.71874 | − 1.855 | 0.005571 | 0.0084046 |
hsa05167 | Kaposi sarcoma-associated herpesvirus infection | 7 | 4 | − 0.72723 | − 1.8713 | 0.0028011 | 0.0085282 |
hsa04064 | NF-kappa B signaling pathway | 8 | 6 | − 0.79671 | − 2.1169 | 0.0013966 | 0.008899 |
hsa04668 | TNF signaling pathway | 9 | 8 | − 0.67798 | − 1.8731 | 0.002751 | 0.0097465 |
hsa05163 | Human cytomegalovirus infection | 5 | 3 | − 0.77931 | − 1.7897 | 0.004644 | 0.017353 |
hsa04620 | Toll-like receptor signaling pathway | 5 | 3 | − 0.74322 | − 1.7044 | 0.01682 | 0.028378 |
hsa05142 | Chagas disease (American trypanosomiasis) | 5 | 3 | − 0.74322 | − 1.7044 | 0.01682 | 0.028378 |
hsa05200 | Pathways in cancer | 7 | 6 | − 0.6674 | − 1.7301 | 0.011561 | 0.029528 |
hsa04932 | Non-alcoholic fatty liver disease (NAFLD) | 5 | 4 | − 0.74563 | − 1.7086 | 0.006006 | 0.032059 |
hsa04625 | C-type lectin receptor signaling pathway | 5 | 3 | − 0.74881 | − 1.7165 | 0.010753 | 0.032259 |
hsa04380 | Osteoclast differentiation | 7 | 7 | − 0.65041 | − 1.6467 | 0.016129 | 0.04088 |