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Table 4 Determinants of global circumferential early diastolic strain rate

From: Characterization of subclinical diastolic dysfunction by cardiac magnetic resonance feature-tracking in adult survivors of non-Hodgkin lymphoma treated with anthracyclines

Independent variables Dependent variable (GCSR-E)
Univariate analysis Multiple analysis (r2 0.44, p < 0.001)
B Coef 95% CI p B Coef 95% CI p
Cumulative dose − 0.04 (− 0.09;− 0.01) 0.029
Time after therapy − 0.06 (− 0.25;0.13) 0.503
Age (years) − 0.75 (− 1.30;0.19) 0.009 − 0.82 (− 1.29;− 0.35) 0.001
Gender (female) 6.09 (− 11.66;23.85) 0.489
Smoking (Yes) − 18.38 (− 69.86;33.08) 0.472
Hypertension (no) 13.08 (− 6.14;32.31) 0.175
Diabetes (no) − 16.32 (− 46.65;14.00) 0.281
Dyslipidemia (no) 1.79 (− 50.08;53.67) 0.944
Prior radiotherapy (no) 9.31 (− 27.78;46.40) 0.612
LVEF 1.64 (0.50;2.79) 0.006
LVMi 0.18 (− 0.67;1.05) 0.663
LGE (no) 8.99 (− 21.71;39.70) 0.555
Native T1 − 0.10 (− 0.36;0.15) 0.424
ECV − 1.07 (− 3.89;1.75) 0.446
T2 1.56 (− 2.87;5.99) 0.478
GCS − 4.37 (− 7.28;− 1.47) 0.004 − 4.74 (− 7.25;− 2.23)  < 0.001
  1. LVEF left ventricular ejection fraction, LVMi left ventricular mass index, LGE late gadolinium enhancement, ECV extracellular volume fraction, GCS global circumferential strain