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Table 4 Determinants of global circumferential early diastolic strain rate

From: Characterization of subclinical diastolic dysfunction by cardiac magnetic resonance feature-tracking in adult survivors of non-Hodgkin lymphoma treated with anthracyclines

Independent variables

Dependent variable (GCSR-E)

Univariate analysis

Multiple analysis (r2 0.44, p < 0.001)

B Coef

95% CI

p

B Coef

95% CI

p

Cumulative dose

− 0.04

(− 0.09;− 0.01)

0.029

–

–

–

Time after therapy

− 0.06

(− 0.25;0.13)

0.503

–

–

–

Age (years)

− 0.75

(− 1.30;0.19)

0.009

− 0.82

(− 1.29;− 0.35)

0.001

Gender (female)

6.09

(− 11.66;23.85)

0.489

–

–

–

Smoking (Yes)

− 18.38

(− 69.86;33.08)

0.472

–

–

–

Hypertension (no)

13.08

(− 6.14;32.31)

0.175

–

–

–

Diabetes (no)

− 16.32

(− 46.65;14.00)

0.281

–

–

–

Dyslipidemia (no)

1.79

(− 50.08;53.67)

0.944

–

–

–

Prior radiotherapy (no)

9.31

(− 27.78;46.40)

0.612

–

–

–

LVEF

1.64

(0.50;2.79)

0.006

–

–

–

LVMi

0.18

(− 0.67;1.05)

0.663

–

–

–

LGE (no)

8.99

(− 21.71;39.70)

0.555

–

–

–

Native T1

− 0.10

(− 0.36;0.15)

0.424

–

–

–

ECV

− 1.07

(− 3.89;1.75)

0.446

–

–

–

T2

1.56

(− 2.87;5.99)

0.478

–

–

–

GCS

− 4.37

(− 7.28;− 1.47)

0.004

− 4.74

(− 7.25;− 2.23)

 < 0.001

  1. LVEF left ventricular ejection fraction, LVMi left ventricular mass index, LGE late gadolinium enhancement, ECV extracellular volume fraction, GCS global circumferential strain
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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