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Table 4 Rhythm control intervention during the follow-up period after LAA closure

From: Atrial fibrillation evolution and rhythm control strategy following left appendage closure: new insights from the prospective FLAAC registry

Age

(range)

Cardiac rhythm before LAA closure

History of thromboembolic event

History of AF ablation

CHA2DS2-VASc score

Procedure of interventional cardiology

Thomboembolic event after cardioversion or an ablation procedure

Antithrombotic treatment before the procedure

Antithrombotic treatment after the procedure

70′s–80′s

Sinus rhythm

No

No

2

Electrical cardioversion

No

VKA

VKA

80′s–90′s

Atrial fibrillation

Yes

No

5

Electrical cardioversion

No

Short term anticoagulation + Antiplatelet therapy

Low Molecular Weight Heparine + Antiplatelet therapy

80′s–90′s

Sinus rhythm

No

No

2

Overdrive pacing

No

Antiplatelet therapy

Antiplatelet therapy

70′s–80′s

Sinus rhythm

No

No

4

Overdrive pacing

No

None

None

70′s–80′s

Sinus rhythm

No

Yes

2

Atrial fibrillation ablation (CP with LAAC, Pulmonary vein isolation)

No

None

DOAC

60′s–70′s

Sinus rhythm

Yes

Yes

5

Left Atrial flutter ablation (Pulmonary vein isolation)

No

Antiplatelet therapy

Antiplatelet therapy

60′s–70′s

Atrial fibrillation

Yes

No

2

Right common flutter ablation (cavotricuspid isthmus ablation)

No

Antiplatelet therapy

Antiplatelet therapy

70′s–80′s

Sinus rhythm

No

No

4

2 ablation procedures: 1) CP with LAAC (cavotricuspid isthmus ablation); 2) Subsequent ablation: (Pulmonary vein isolation)

No

None

VKA

Antiplatelet therapy

None

50′s–60′s

Atrial fibrillation

Yes

No

3

Atrial fibrillation ablation (pulmonary vein isolation isolation) and right common flutter ablation (cavotricuspid isthmus ablation)

No

DOAC + Antiplatelet therapy

DOAC + Antiplatelet therapy

60′s–70′s

Sinus rhythm

Yes

Yes

4

Atrial fibrillation ablation (CP with LAAC, Pulmonary vein isolation)

No

DOAC

DOAC

60′s–70′s

Sinus rhythm

No

No

1

Atrial fibrillation ablation (CP with LAAC, Pulmonary vein isolation)

No

Antiplatelet therapy

Low Molecular Weight Heparine + Antiplatelet therapy

60′s–70′s

Sinus rhythm

No

No

2

Atrial fibrillation ablation (CP with LAAC, Pulmonary vein isolation)

No

Antiplatelet therapy + VKA

Antiplatelet therapy + VKA

60′s–70′s

Sinus rhythm

No

Yes

2

Atrial fibrillation ablation (CP with LAAC, Pulmonary vein isolation)

No

None

Low Molecular Weight Heparine + Antiplatelet therapy

  1. CP with LAAC, Catheter ablation combined with left atrial appendage closure; DOAC, Direct Oral Anticoagulant; VKA, vitamin K antagonist