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Table 3 Comparison of echocardiographic parameters between the groups with and without inhaled nitric oxide

From: Inhaled nitric oxide preserves ventricular function during resuscitation using a percutaneous mechanical circulatory support device in a porcine cardiac arrest model: an echocardiographic myocardial work analysis

  0 ppm 20 ppm Total p
Baseline
RVD1 cm 3.1 ± 0.4 3.4 ± 0.4 3.3 ± 0.4 0.332
RVD2 cm 2.6 ± 0.2 2.7 ± 0.4 2.6 ± 0.3 0.417
RVD3 cm 4.0 ± 0.2 3.8 ± 0.4 3.9 ± 0.3 0.424
RV-FAC % 44.1 ± 6.0 42.9 ± 6.6 43.5 ± 6.0 0.772
LVEDV mL 70.5 ± 3.5 70.9 ± 6.1 70.7 ± 4.7 0.911
LVESV mL 31.9 ± 4.6 33.4 ± 3.6 32.6 ± 4.0 0.583
LV-EF % 61.5 ± 5.8 64.7 ± 9.2 63.1 ± 7.5 0.525
LV-GLS % − 21.0 ± 5.1 − 21.6 ± 3.4 − 21.3 ± 4.1 0.833
LV-GWI mmHg% 1835.3 ± 306.2 1751 ± 270.2 3444.3 ± 5242.8 0.336
LV-GCW mmHg% 2095.8 ± 527.4 2103.2 ± 405.8 2099.5 ± 443.6 0.981
LV-GWW mmHg% 368.0 ± 208.8 352.4 ± 115.9 360.2 ± 159.4 0.887
LV-GWE % 85.2 ± 4.7 80.0 ± 1.4 82.6 ± 4.2 0.054
TASV cm/sec 13.6 ± 1.1 13.8 ± 1.5 13.7 ± 1.3 0.817
RV-GLS % − 16.4 ± 3.2 − 14.4 ± 1.8 − 15.4 ± 2.7 0.267
RV-GWI mmHg% 338.2 ± 45.3 286.8 ± 57.5 312.5 ± 55.8 0.155
RV-GCW mmHg% 376.4 ± 92.6 266.6 ± 41.1 321.5 ± 89.0 0.082
RV-GWW mmHg% 61.6 ± 13.8 55.4 ± 10.6 58.5 ± 12.1 0.949
RV-GWE % 79.8 ± 10.2 80.8 ± 6.1 80.3 ± 7.9 0.855
Cardiac arrest
RVD1 cm 4.0 ± 0.3 4.2 ± 0.3 4.1 ± 0.3 0.397
RVD2 cm 3.3 ± 0.6 3.5 ± 0.4 3.4 ± 0.5 0.581
RVD3 cm 4.5 ± 0.2 4.6 ± 0.5 4.6 ± 0.4 0.749
RVEDA cm2 13.9 ± 1.6 15.2 ± 1.1 14.6 ± 1.4 0.183
LVEDV mL 81.0 ± 4.9 76.6 ± 7.5 78.8 ± 6.4 0.306
30 min. post-ROSC
RVD1 cm 3.7 ± 0.3 3.6 ± 0.4 3.7 ± 0.3 0.582
RVD2 cm 3.0 ± 0.4 2.9 ± 0.4 2.9 ± 0.4 0.716
RVD3 cm 4.5 ± 0.2 4.6 ± 0.1 4.5 ± 0.2 0.776
RV-FAC % 27.4 ± 2.8 32.0 ± 9.3 30.5 ± 6.5 0.494
LVEDV mL 77.0 ± 6.5 73.8 ± 9.7 75.4 ± 8.0 0.558
LVESV mL 35.8 ± 5.1 35.4 ± 3.7 35.6 ± 4.2 0.897
LVEF % 47.6 ± 5.0 42.0 ± 8.1 44.8 ± 7.0 0.225
LV-GLS % − 11.6 ± 3.3 − 13.2 ± 4.7 − 12.4 ± 3.9 0.548
LV-GWI mmHg% 891.2 ± 412.7 1201.8 ± 400.5 1046.5 ± 416.8 0.262
LV-GCW mmHg% 719.0 ± 497.8 919.6 ± 638.2 819.3 ± 549.8 0.595
LV-GWW mmHg% 360.4 ± 271.1 240.2 ± 148.1 300.3 ± 215.4 0.416
LV-GWE % 63.4 ± 7.7 75.0 ± 8.7 69.2 ± 9.9 0.256
TASV cm/sec 10.4 ± 4.9 9.8 ± 1.8 10.1 ± 3.5 0.803
RV-GLS % − 6.6 ± 3.3 − 9.4 ± 2.9 − 8.0 ± 3.3 0.193
RV-GWI mmHg% 101.6 ± 34.5 92.0 ± 33.3 96.8 ± 32.4 0.666
RV-GCW mmHg% 152.2 ± 15.5 159.6 ± 20.2 164.1 ± 40.0 0.395
RV-GWW mmHg% 59.4 ± 11.9 49.4 ± 9.1 52.3 ± 13.2 0.843
RV-GWE % 70.6 ± 12.0 74.0 ± 8.6 72.3 ± 10.0 0.621
3 h. post-ROSC
RVD1 cm 3.3 ± 0.3 3.4 ± 0.3 3.4 ± 0.3 0.782
RVD2 cm 2.7 ± 0.3 2.8 ± 0.1 2.8 ± 0.2 0.347
RVD3 cm 4.4 ± 0.1 4.3 ± 0.3 4.3 ± 0.2 0.718
RV-FAC % 32.5 ± 5.0 43.3 ± 7.0 43.2 ± 6.8 0.945
LVEDV mL 78.2 ± 1.1 70.8 ± 1.3 74.5 ± 4.1  < 0.001
LVESV mL 38.0 ± 4.9 35.2 ± 3.5 36.6 ± 4.3 0.342
LVEF % 61.5 ± 5.8 64.7 ± 9.2 63.1 ± 7.5 0.525
LV-GLS % − 12.2 ± 2.8 − 16.0 ± 2.3 − 14.1 ± 3.1 0.058
LV-GWI mmHg% 896.2 ± 129.3 1399.2 ± 347.3 1147.7 ± 362.4 0.116
LV-GCW mmHg% 719.0 ± 497.8 1598.8 ± 849.2 1158.9 ± 803.5 0.081
LV-GWW mmHg% 264.6 ± 78.9 293.4 ± 212.5 279.0 ± 151.9 0.784
LV-GWE % 67.2 ± 3.3 81.4 ± 5.6 74.3 ± 8.7 0.010
TASV cm/sec 7.8 ± 1.6 11.4 ± 1.1 11.0 ± 1.5 0.024
RV-GLS % − 10.0 ± 1.0 − 12.0 ± 2.7 − 11.0 ± 2.2 0.164
RV-GWI mmHg% 108.4 ± 22.6 189.6 ± 43.6 149.0 ± 53.9 0.049
RV-GCW mmHg% 203.4 ± 39.6 221.2 ± 85.6 212.3 ± 63.6 0.684
RV-GWW mmHg% 69.6 ± 11.9 47.4 ± 6.7 47.8 ± 13.3 0.049
RV-GWE % 72.2 ± 14.0 75.0 ± 11.1 73.6 ± 12.0 0.734
5 h post-ROSC
RVD1 cm 3.5 ± 0.5 3.9 ± 0.7 3.7 ± 0.6 0.308
RVD2 cm 2.8 ± 0.4 3.2 ± 0.7 3.0 ± 0.6 0.287
RVD3 cm 4.4 ± 0.2 4.6 ± 0.1 4.5 ± 0.2 0.024
RV-FAC % 33.2 ± 4.3 41.1 ± 6.5 37.1 ± 6.7 0.053
LVEDV mL 70.8 ± 1.3 68.2 ± 2.7 69.5 ± 2.4 0.087
LVESV mL 38.0 ± 6.9 35.6 ± 4.5 36.8 ± 5.6 0.525
LVEF % 51.4 ± 3.0 57.0 ± 6.2 54.2 ± 5.5 0.108
LV-GLS % − 13.0 ± 2.4 − 18.2 ± 3.4 − 15.6 ± 3.9 0.036
LV-GWI mmHg% 1125 ± 214 1529.2 ± 274.5 1251.3 ± 348.4 0.052
LV-GCW mmHg% 1203.8 ± 253.0 1728.4 ± 466.7 1466.1 ± 449.1 0.058
LV-GWW mmHg% 395.4 ± 159.4 367.0 ± 87.2 381.2 ± 122.1 0.736
LV-GWE % 75.8 ± 2.3 82.6 ± 4.0 79.2 ± 4.7 0.071
TASV cm/s 9.4 ± 1.3 12.8 ± 1.1 9.9 ± 2.2 0.012
RV-GLS % − 9.0 ± 1.4 − 13.2 ± 2.2 − 11.1 ± 2.8 0.040
RV-GWI mmHg% 152.6 ± 42.4 261.6 ± 54.2 207.1 ± 73.5 0.041
RV-GCW mmHg% 224.4 ± 158.7 212.6 ± 53.8 218.5 ± 111.9 0.879
RV-GWW mmHg% 77.8 ± 14.8 50.2 ± 8.2 61.4 ± 22.4 0.046
RV-GWE % 68 ± 5.7 80 ± 5.2 76 ± 5.4 0.042
  1. GCW: Global constructed myocardial work; GLS: Global longitudinal strain; GWE: Global myocardial work efficiency; GWI: Global myocardial work index; GWW: Global wasted work; LV: Left ventricle; LVEDV: Left ventricle end-diastolic volume; LVEF: Left ventricular ejection fraction; LVESV: Left ventricular end-systolic volume; RVEDA: right ventricle end-diastolic area; RVD1: right ventricle basal diameter from apical 4 chamber view; RVD2: right ventricular mid diameter at midlevel from apical 4 chamber view; RVD3: right ventricle longitudinal diameter; RV-FAC: right ventricular fractional area change; TASV: TASV: Tricuspid annular systolic velocity