| |
0 ppm
|
20 ppm
|
Total
|
p
|
|---|
|
Baseline
|
|
RVD1 cm
|
3.1 ± 0.4
|
3.4 ± 0.4
|
3.3 ± 0.4
|
0.332
|
|
RVD2 cm
|
2.6 ± 0.2
|
2.7 ± 0.4
|
2.6 ± 0.3
|
0.417
|
|
RVD3 cm
|
4.0 ± 0.2
|
3.8 ± 0.4
|
3.9 ± 0.3
|
0.424
|
|
RV-FAC %
|
44.1 ± 6.0
|
42.9 ± 6.6
|
43.5 ± 6.0
|
0.772
|
|
LVEDV mL
|
70.5 ± 3.5
|
70.9 ± 6.1
|
70.7 ± 4.7
|
0.911
|
|
LVESV mL
|
31.9 ± 4.6
|
33.4 ± 3.6
|
32.6 ± 4.0
|
0.583
|
|
LV-EF %
|
61.5 ± 5.8
|
64.7 ± 9.2
|
63.1 ± 7.5
|
0.525
|
|
LV-GLS %
|
− 21.0 ± 5.1
|
− 21.6 ± 3.4
|
− 21.3 ± 4.1
|
0.833
|
|
LV-GWI mmHg%
|
1835.3 ± 306.2
|
1751 ± 270.2
|
3444.3 ± 5242.8
|
0.336
|
|
LV-GCW mmHg%
|
2095.8 ± 527.4
|
2103.2 ± 405.8
|
2099.5 ± 443.6
|
0.981
|
|
LV-GWW mmHg%
|
368.0 ± 208.8
|
352.4 ± 115.9
|
360.2 ± 159.4
|
0.887
|
|
LV-GWE %
|
85.2 ± 4.7
|
80.0 ± 1.4
|
82.6 ± 4.2
|
0.054
|
|
TASV cm/sec
|
13.6 ± 1.1
|
13.8 ± 1.5
|
13.7 ± 1.3
|
0.817
|
|
RV-GLS %
|
− 16.4 ± 3.2
|
− 14.4 ± 1.8
|
− 15.4 ± 2.7
|
0.267
|
|
RV-GWI mmHg%
|
338.2 ± 45.3
|
286.8 ± 57.5
|
312.5 ± 55.8
|
0.155
|
|
RV-GCW mmHg%
|
376.4 ± 92.6
|
266.6 ± 41.1
|
321.5 ± 89.0
|
0.082
|
|
RV-GWW mmHg%
|
61.6 ± 13.8
|
55.4 ± 10.6
|
58.5 ± 12.1
|
0.949
|
|
RV-GWE %
|
79.8 ± 10.2
|
80.8 ± 6.1
|
80.3 ± 7.9
|
0.855
|
|
Cardiac arrest
|
|
RVD1 cm
|
4.0 ± 0.3
|
4.2 ± 0.3
|
4.1 ± 0.3
|
0.397
|
|
RVD2 cm
|
3.3 ± 0.6
|
3.5 ± 0.4
|
3.4 ± 0.5
|
0.581
|
|
RVD3 cm
|
4.5 ± 0.2
|
4.6 ± 0.5
|
4.6 ± 0.4
|
0.749
|
|
RVEDA cm2
|
13.9 ± 1.6
|
15.2 ± 1.1
|
14.6 ± 1.4
|
0.183
|
|
LVEDV mL
|
81.0 ± 4.9
|
76.6 ± 7.5
|
78.8 ± 6.4
|
0.306
|
|
30 min. post-ROSC
|
|
RVD1 cm
|
3.7 ± 0.3
|
3.6 ± 0.4
|
3.7 ± 0.3
|
0.582
|
|
RVD2 cm
|
3.0 ± 0.4
|
2.9 ± 0.4
|
2.9 ± 0.4
|
0.716
|
|
RVD3 cm
|
4.5 ± 0.2
|
4.6 ± 0.1
|
4.5 ± 0.2
|
0.776
|
|
RV-FAC %
|
27.4 ± 2.8
|
32.0 ± 9.3
|
30.5 ± 6.5
|
0.494
|
|
LVEDV mL
|
77.0 ± 6.5
|
73.8 ± 9.7
|
75.4 ± 8.0
|
0.558
|
|
LVESV mL
|
35.8 ± 5.1
|
35.4 ± 3.7
|
35.6 ± 4.2
|
0.897
|
|
LVEF %
|
47.6 ± 5.0
|
42.0 ± 8.1
|
44.8 ± 7.0
|
0.225
|
|
LV-GLS %
|
− 11.6 ± 3.3
|
− 13.2 ± 4.7
|
− 12.4 ± 3.9
|
0.548
|
|
LV-GWI mmHg%
|
891.2 ± 412.7
|
1201.8 ± 400.5
|
1046.5 ± 416.8
|
0.262
|
|
LV-GCW mmHg%
|
719.0 ± 497.8
|
919.6 ± 638.2
|
819.3 ± 549.8
|
0.595
|
|
LV-GWW mmHg%
|
360.4 ± 271.1
|
240.2 ± 148.1
|
300.3 ± 215.4
|
0.416
|
|
LV-GWE %
|
63.4 ± 7.7
|
75.0 ± 8.7
|
69.2 ± 9.9
|
0.256
|
|
TASV cm/sec
|
10.4 ± 4.9
|
9.8 ± 1.8
|
10.1 ± 3.5
|
0.803
|
|
RV-GLS %
|
− 6.6 ± 3.3
|
− 9.4 ± 2.9
|
− 8.0 ± 3.3
|
0.193
|
|
RV-GWI mmHg%
|
101.6 ± 34.5
|
92.0 ± 33.3
|
96.8 ± 32.4
|
0.666
|
|
RV-GCW mmHg%
|
152.2 ± 15.5
|
159.6 ± 20.2
|
164.1 ± 40.0
|
0.395
|
|
RV-GWW mmHg%
|
59.4 ± 11.9
|
49.4 ± 9.1
|
52.3 ± 13.2
|
0.843
|
|
RV-GWE %
|
70.6 ± 12.0
|
74.0 ± 8.6
|
72.3 ± 10.0
|
0.621
|
|
3 h. post-ROSC
|
|
RVD1 cm
|
3.3 ± 0.3
|
3.4 ± 0.3
|
3.4 ± 0.3
|
0.782
|
|
RVD2 cm
|
2.7 ± 0.3
|
2.8 ± 0.1
|
2.8 ± 0.2
|
0.347
|
|
RVD3 cm
|
4.4 ± 0.1
|
4.3 ± 0.3
|
4.3 ± 0.2
|
0.718
|
|
RV-FAC %
|
32.5 ± 5.0
|
43.3 ± 7.0
|
43.2 ± 6.8
|
0.945
|
|
LVEDV mL
|
78.2 ± 1.1
|
70.8 ± 1.3
|
74.5 ± 4.1
|
< 0.001
|
|
LVESV mL
|
38.0 ± 4.9
|
35.2 ± 3.5
|
36.6 ± 4.3
|
0.342
|
|
LVEF %
|
61.5 ± 5.8
|
64.7 ± 9.2
|
63.1 ± 7.5
|
0.525
|
|
LV-GLS %
|
− 12.2 ± 2.8
|
− 16.0 ± 2.3
|
− 14.1 ± 3.1
|
0.058
|
|
LV-GWI mmHg%
|
896.2 ± 129.3
|
1399.2 ± 347.3
|
1147.7 ± 362.4
|
0.116
|
|
LV-GCW mmHg%
|
719.0 ± 497.8
|
1598.8 ± 849.2
|
1158.9 ± 803.5
|
0.081
|
|
LV-GWW mmHg%
|
264.6 ± 78.9
|
293.4 ± 212.5
|
279.0 ± 151.9
|
0.784
|
|
LV-GWE %
|
67.2 ± 3.3
|
81.4 ± 5.6
|
74.3 ± 8.7
|
0.010
|
|
TASV cm/sec
|
7.8 ± 1.6
|
11.4 ± 1.1
|
11.0 ± 1.5
|
0.024
|
|
RV-GLS %
|
− 10.0 ± 1.0
|
− 12.0 ± 2.7
|
− 11.0 ± 2.2
|
0.164
|
|
RV-GWI mmHg%
|
108.4 ± 22.6
|
189.6 ± 43.6
|
149.0 ± 53.9
|
0.049
|
|
RV-GCW mmHg%
|
203.4 ± 39.6
|
221.2 ± 85.6
|
212.3 ± 63.6
|
0.684
|
|
RV-GWW mmHg%
|
69.6 ± 11.9
|
47.4 ± 6.7
|
47.8 ± 13.3
|
0.049
|
|
RV-GWE %
|
72.2 ± 14.0
|
75.0 ± 11.1
|
73.6 ± 12.0
|
0.734
|
|
5 h post-ROSC
|
|
RVD1 cm
|
3.5 ± 0.5
|
3.9 ± 0.7
|
3.7 ± 0.6
|
0.308
|
|
RVD2 cm
|
2.8 ± 0.4
|
3.2 ± 0.7
|
3.0 ± 0.6
|
0.287
|
|
RVD3 cm
|
4.4 ± 0.2
|
4.6 ± 0.1
|
4.5 ± 0.2
|
0.024
|
|
RV-FAC %
|
33.2 ± 4.3
|
41.1 ± 6.5
|
37.1 ± 6.7
|
0.053
|
|
LVEDV mL
|
70.8 ± 1.3
|
68.2 ± 2.7
|
69.5 ± 2.4
|
0.087
|
|
LVESV mL
|
38.0 ± 6.9
|
35.6 ± 4.5
|
36.8 ± 5.6
|
0.525
|
|
LVEF %
|
51.4 ± 3.0
|
57.0 ± 6.2
|
54.2 ± 5.5
|
0.108
|
|
LV-GLS %
|
− 13.0 ± 2.4
|
− 18.2 ± 3.4
|
− 15.6 ± 3.9
|
0.036
|
|
LV-GWI mmHg%
|
1125 ± 214
|
1529.2 ± 274.5
|
1251.3 ± 348.4
|
0.052
|
|
LV-GCW mmHg%
|
1203.8 ± 253.0
|
1728.4 ± 466.7
|
1466.1 ± 449.1
|
0.058
|
|
LV-GWW mmHg%
|
395.4 ± 159.4
|
367.0 ± 87.2
|
381.2 ± 122.1
|
0.736
|
|
LV-GWE %
|
75.8 ± 2.3
|
82.6 ± 4.0
|
79.2 ± 4.7
|
0.071
|
|
TASV cm/s
|
9.4 ± 1.3
|
12.8 ± 1.1
|
9.9 ± 2.2
|
0.012
|
|
RV-GLS %
|
− 9.0 ± 1.4
|
− 13.2 ± 2.2
|
− 11.1 ± 2.8
|
0.040
|
|
RV-GWI mmHg%
|
152.6 ± 42.4
|
261.6 ± 54.2
|
207.1 ± 73.5
|
0.041
|
|
RV-GCW mmHg%
|
224.4 ± 158.7
|
212.6 ± 53.8
|
218.5 ± 111.9
|
0.879
|
|
RV-GWW mmHg%
|
77.8 ± 14.8
|
50.2 ± 8.2
|
61.4 ± 22.4
|
0.046
|
|
RV-GWE %
|
68 ± 5.7
|
80 ± 5.2
|
76 ± 5.4
|
0.042
|
- GCW: Global constructed myocardial work; GLS: Global longitudinal strain; GWE: Global myocardial work efficiency; GWI: Global myocardial work index; GWW: Global wasted work; LV: Left ventricle; LVEDV: Left ventricle end-diastolic volume; LVEF: Left ventricular ejection fraction; LVESV: Left ventricular end-systolic volume; RVEDA: right ventricle end-diastolic area; RVD1: right ventricle basal diameter from apical 4 chamber view; RVD2: right ventricular mid diameter at midlevel from apical 4 chamber view; RVD3: right ventricle longitudinal diameter; RV-FAC: right ventricular fractional area change; TASV: TASV: Tricuspid annular systolic velocity
