Fig. 1

The up-regulation of miR-200 family members in EAT from CAD patients. a The Volcano plot of miRNA expression fold change between CAD and CON (x axis, log2 fold change; y axis, p value significance). Up-regulated genes (Log2 FC > 1) in CAD samples are indicated by a red dot, and Down-regulated genes (Log2 FC < − 1) in CAD samples are indicated by a green dot. b Heat-map of the 250 differentially expressed transcripts. Red color indicated higher expression level; green color indicated lower expression level. c–g The expression levels of hsa-miR-200a-3p (c), hsa-miR-200b-3p (D), hsa-miR-200c-3p (e), hsa-miR-141-3p (f) and hsa-miR-429 (g) in EAT from CAD patients (n = 16) and CON patients (n = 5) were accessed by qRT-PCR, and normalized with U6. Unpaired t test was used for comparison between groups