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Table 4 Reclassification and predictive potential value of VVV for childhood HBP

From: School-based surveillance on visit-to-visit blood pressure variability and high blood pressure in children and adolescents

HBP C-statistics Continuous NRI, % IDI, %
Estimate (95% Cl) P value Estimate P value Estimate P value
Model 3 0.803 (0.798–0.805)   Reference   Reference  
Model 3 + SBP-SDa 0.847 (0.842–0.853) < 0.0001 65.57% < 0.0001 4.71% < 0.0001
Model 3 + SBP-ARVa 0.848 (0.843–0.853) < 0.0001 62.69% < 0.0001 5.59% 0.003
Model 3 + DBP-SDa 0.822 (0.818–0.826) < 0.0001 38.02% < 0.0001 1.51% < 0.0001
Model 3 + DBP-ARVa 0.822 (0.818–0.826) < 0.0001 37.56% < 0.0001 1.86% 0.003
  1. Model 3 included age and BMI in 2018, sex, SES, region, mean SBP and DBP z-scores during 2012–2017, and BP measurement times
  2. HBP, high blood pressure; DBP, diastolic blood pressure; SBP, systolic blood pressure; SD, standard deviation; ARV, actual real variability; CV, coefficient of variation; NRI, net reclassification index; IDI, integrated discrimination improvement
  3. aBP variability parameters were calculated based on BP z-scores during 2012–2017