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Table 1 Timeline

From: Delayed diagnosis of dilated thyrotoxic cardiomyopathy with coexistent multifocal atrial tachycardia: a case report

Timeline

 

14 days prior to presentation

The patient experienced diarrhoea and nausea

10 days prior to presentation

She began to feel dyspnoea on effort

4 days prior to presentation

She experienced worsening dyspnoea and a nonproductive cough on deep breathing

On emergent presentation

 

6:40:00 PM

She presented with worsening dyspnoea at the emergency department. Electrocardiogram showed MAT. Echocardiography revealed left ventricular dilatation and severe hypokinesis; the patient was diagnosed with dilated cardiomyopathy

6:44:00 PM

She was treated for MAT with intravenous administration of adenosine triphosphate, verapamil, and landiolol, as well as multiple cardioversions, which were ineffective

8:12:00 PM

She rapidly progressed to cardiogenic shock and respiratory decompensation, which required intubation and inotropic support

9:35:00 PM

Emergent coronary angiography was unremarkable. An IABP was inserted

11:59:00 PM

Amiodarone was started for refractory MAT

Day 3

IABP and administration of amiodarone successfully suppressed the recurrence of MAT

Day 5

She was weaned from the vasoactive agents, and anti-failure therapy was carefully induced

Day 7

She was weaned off IABP

Day 8

Endomyocardial biopsy was performed

A workup for the unexplained tachycardia led to the correct diagnosis of thyroid storm

Day 11

Extubation and cardiac rehabilitation

Day 31

Thiamazole was induced

Day 38

Follow-up echocardiography demonstrated significant improvements in left ventricular systolic function and reverse remodelling

Day 40

Discharged to home

Regular follow-up

She received treatment at our outpatient clinic to establish clinical euthyroidism

Day 131

Total thyroidectomy was performed; thyroid pathology was consistent with Graves' disease

6-month follow-up

48-month follow-up

Full recovery of the LVSD was observed

She remained clinically stable

  1. MAT: Multifocal atrial tachycardia, IABP: Intra-aortic balloon pump, LVSD: Left ventricular systolic dysfunction