Table 1 Baseline characteristics of the studied population sample
From: IGFBP-1 and IGFBP-2 are associated with a decreased pulse-wave velocity in young, healthy adults
Men (n = 257) | Non-estrogen using women (n = 427) | Estrogen using women (n = 149) | p value M vs NEU | p value M vs EU | p value NEU vs EU | |
|---|---|---|---|---|---|---|
Age | 22 ± 2.0 | 22 ± 2.0 | 22 ± 1.6 | 0.69 | 0.27 | 0.58 |
Body fat (%) | 15 ± 5.6 | 28 ± 6.8 | 27 ± 5.9 | < 0.001 | < 0.001 | 0.42 |
LDL (mmol/L) | 2.3 ± 0.69 | 2.2 ± 0.69 | 2.5 ± 0.79 | 0.36 | < 0.001 | < 0.001 |
HDL (mmol/L) | 1.2 ± 0.28 | 1.4 ± 0.35 | 1.5 ± 0.41 | < 0.001 | < 0.001 | 0.81 |
CHOL (mmol/L) | 4.0 ± 0,79 | 4.3 ± 0.77 | 4.4 ± 0.77 | 0.0034 | < 0.001 | 0.0042 |
Systolic BP (mmHg) | 122 ± 11 | 109 ± 9.0 | 112 ± 7.5 | < 0.001 | < 0.001 | 0.0034 |
Diastolic BP (mmHg) | 64 ± 6.7 | 64 ± 6.0 | 65 ± 6.9 | 0.089 | 0.75 | 0.015 |
TG (mmol/L) | 0.79 ± 0.35 | 0.75 ± 0.32 | 0.99 ± 0.39 | 0.25 | < 0.001 | < 0.001 |
Fasting serum insulin (mIE/L) | 7.5 ± 3.7 | 8.1 ± 4.7 | 8.2 ± 4.4 | 0.32 | 0.56 | 0.99 |
HOMA-IR | 1.8 ± 0.90 | 1.8 ± 1.1 | 1.7 ± 0.93 | 0.95 | 0.99 | 0.96 |
Apo B (g/L) | 0.77 ± 0.18 | 0.78 ± 0.18 | 0.83 ± 0.20 | 0.97 | < 0.001 | < 0.001 |
Apo A-1 (g/L) | 1.4 ± 0.21 | 1.5 ± 0.27 | 1.7 ± 0.325 | < 0.001 | < 0.001 | < 0.001 |
Apo B/Apo A-1 ratio | 0.56 ± 0.14 | 0.51 ± 0.14 | 0.50 ± 0.15 | < 0.001 | 0.032 | 0.75 |
CRP (mg/L) | 1.3 ± 2.7 | 1.4 ± 2.8 | 4.1 ± 7.1 | 0.99 | < 0.001 | < 0.001 |
PWV (m/s) | 5.6 ± 0.86 | 5.2 ± 0.69 | 5.3 ± 0.9 | < 0.001 | 0.092 | 0.0045 |
AIX (%) | − 8.4 ± 9.5 | − 5.0 ± 10 | − 4.7 ± 9.1 | < 0.001 | 0.0019 | 0.99 |
cIMT (mm) | 0.60 ± 0.073 | 0.49 ± 0.057 | 0.50 ± 0.055 | 0.48 | 0.18 | 0.61 |
PC 1 | 0.64 ± 0.75 | − 0.020 ± 0.87 | − 1.0 ± 0.85 | < 0.001 | < 0.001 | < 0.001 |
PC 2 | 0.032 ± 0.97 | 0.036 ± 1.1 | − 0.16 ± 0.86 | 0.99 | 0.29 | 0.21 |
PC 3 | − 0.52 ± 0.78 | − 0.068 ± 0.86 | 1.1 ± 0.87 | < 0.001 | < 0.001 | < 0.001 |