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Table 1 Baseline profile of the Thalassaemia Major patients group according to CMR-T2* values

From: Left ventricular deformation mechanics over time in patients with thalassemia major with and without iron overload

  Group1 (n = 32) Group2 (n = 8) P
Age 42 ± 4 39 ± 8 0.45
BSA (m2) 1.69 ± 0.12 1.67 ± 0.23 0.75
Pure RBC (ml/kg/yr) 185 ± 60 199 ± 37 0.64
Serum ferritin (mg/L) 1217 ± 1804 3663 ± 4204 0.02
Cardiac T2* (ms) 33 ± 3 16 ± 9 0.01
Liver T2* (ms) 4 ± 5 17 ± 21 0.01
Splenectomy (n) 12 2 0.68
Diabetes (n) 7 0 0.18
Medication (n)    0.02
 Chelators    
 Deferoxamine 5 2  
 Deferasirox 13 1  
 Deferiprone 4 0  
 Deferoxamine + Deferasirox 0 2  
 Deferoxamine + Deferiprone 10 3  
Beta-blockers 4 2 0.28
ACEI/ARB 2 1 0.46
  1. ACEI ACE inhibitors, ARB angiotensin receptor blockers, BSA body surface area, CMR Cardiac Magnetic Resonance, LIC liver iron concentration, RBC red blood cells