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Table 1 Baseline profile of the Thalassaemia Major patients group according to CMR-T2* values

From: Left ventricular deformation mechanics over time in patients with thalassemia major with and without iron overload

 

Group1 (n = 32)

Group2 (n = 8)

P

Age

42 ± 4

39 ± 8

0.45

BSA (m2)

1.69 ± 0.12

1.67 ± 0.23

0.75

Pure RBC (ml/kg/yr)

185 ± 60

199 ± 37

0.64

Serum ferritin (mg/L)

1217 ± 1804

3663 ± 4204

0.02

Cardiac T2* (ms)

33 ± 3

16 ± 9

0.01

Liver T2* (ms)

4 ± 5

17 ± 21

0.01

Splenectomy (n)

12

2

0.68

Diabetes (n)

7

0

0.18

Medication (n)

  

0.02

 Chelators

   

 Deferoxamine

5

2

 

 Deferasirox

13

1

 

 Deferiprone

4

0

 

 Deferoxamine + Deferasirox

0

2

 

 Deferoxamine + Deferiprone

10

3

 

Beta-blockers

4

2

0.28

ACEI/ARB

2

1

0.46

  1. ACEI ACE inhibitors, ARB angiotensin receptor blockers, BSA body surface area, CMR Cardiac Magnetic Resonance, LIC liver iron concentration, RBC red blood cells
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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