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Table 4 The distribution of combined genotypes of CYP2C9 and AGTR1 in Han Chinese hypertensive patients

From: Distributive characteristics of the CYP2C9 and AGTR1 genetic polymorphisms in Han Chinese hypertensive patients: a retrospective study

CYP2C9 genotype AGTR1 genotype Reactions for β-receptors blockers Expected efficacy Expected adverse reactions Frequencies
Metabolizing capacity Sensitivity
*1/*1 AA EM Normal +   84.66% (2048)
*1/*1 AC EM Slightly increased ++   8.43% (204)
*1/*1 CC EM Significantly increased ++   0.21% (5)
*1/*3 AA IM Normal ++   5.46% (132)
*1/*3 AC IM Slightly increased +++   0.87% (21)
*1/*3 CC IM Significantly increased +++ + 0.08% (2)
*3/*3 AA PM Normal +++   0.29% (7)
*3/*3 AC PM Slightly increased +++ + 0
*3/*3 CC PM Significantly increased +++ ++ 0