Table 3 Three-level models for OS of CHF-PRO for patients with CHF

Fixed effects

Intercept

238.22 (0.50)

218.60 (1.13)

207.40 (3.27)

Time

8.60 (0.36)*

4.58 (0.39)*

Age

− 0.17 (0.03)*

Female

− 1.66 (0.77)*

NYHA

− 4.15 (0.45)*

Regular schedule

3.66 (0.45)*

Avoid over-eating

4.13 (0.55)*

Low-sodium diet

1.71 (0.40)*

Exercises

2.84 (0.28)*

Random effects

Level 2 (subjects)

 (Intercept)

41.20 (9.17)

384.07 (44.86)*

405.87 (40.26)*

 (Time)

20.33 (4.61)*

27.46 (4.12)*

Level 1 (time point)

 (Intercept)

342.10 (13.04)

197.15 (9.05)*

146.74 (6.73)*

− 2 Log likelihood

16,844.48

16,159.17

15,651.74