Associations between hyperhomocysteinemia and the presence and severity of acute coronary syndrome in young adults ≤ 35 years of age

Table 2 Univariate logistic regression analysis of the association of ACS with variables

Variables	OR	95% Cl	P
Age	0.970	0.925–1.017	0.206
Male	3.628	2.199–5.985	< 0.001
BMI	1.104	1.067–1.142	< 0.001
eGFR	1.005	0.999–1.012	0.101
Drinker	0.851	0.604–1.200	0.357
Smoker	2.186	1.655–2.188	< 0.001
Hypertension	1.712	1.287–2.277	< 0.001
Diabetes mellitus	2.875	1.783–4.634	< 0.001
Hypertriglyceridemia	2.717	2.038–3.622	< 0.001
Hypercholesterolemia	1.930	1.380–2.700	< 0.001
High LDL-C	2.105	1.475–3.005	< 0.001
Low HDL-C	2.322	1.756–3.070	< 0.001
Family history of CAD	1.704	1.073–2.706	0.024
Familial hypercholesterolemia	8.531	1.15–63.252	0.036
Hyperuricemia	1.461	1.101–1.938	0.009
Hyperhomocysteinemia	4.615	3.408–6.250	< 0.001

CAD coronary artery disease, ACS acute coronary syndrome, BMI body mass index, eGFR estimated glomerular filtration rate, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, OR odds ratio, CI confidence interval
Bold values indicate statistical significance

ISSN: 1471-2261