Table 2 Comparison of demographics and clinical characteristics between two clinics

Age (years), median (IQR)

78 (68–84)

80 (72–85)

73 (62–81)

 < .001***

Age group (years)

 (< 40)

26 (2.2)

10 (1.4)

16 (3.5)

 (40–50)

49 (4.1)

13 (2.0)

36 (8.0)

  (50–60)

98 (8.3)

41 (6.0)

57 (12.4)

 (60–70)

180 (15.2)

92 (13.0)

88 (19.1)

 < .001***

 (70–80)

380 (32.1)

242 (33.5)

138 (28)

 (> 80)

451 (38.1)

325 (45.0)

126 (27.3)

Sex, n (%)

 Male

671 (57.0)

364 (50.3)

307 (67.0)

 < .001***

Weight (kg), median (IQR)

77 (65–91.2)

76.34 (63–90)

78 (66–95)

.072

Systolic blood pressure (mmHg), median (IQR)

120 (106–135)

123 (110–140)

112 (100–130)

 < .001***

Diastolic blood pressure (mmHg), median (IQR)

65 (60–75)

67 (59–76)

60 (60–71.5)

.010*

Heart rate (beats/min), median (IQR)

70 (60–80)

70 (60–81)

70 (60–80)

.303

Number of medications used, median (IQR)

10 (8–13)

11 (8–14)

9.0 (7.0–12)

 < .001***

 Non-polypharmacy (0–4 drugs)

44 (4.2)

21 (4.0)

23 (5.0)

 Polypharmacy (5–9 drugs)

406 (39.2)

184 (32.0)

222 (48.3)

 < .001***

 Hyper polypharmacy (≥ 10 drugs)

586 (57.0)

371 (64.4)

215 (47.0)

Biochemical parameters

 Serum creatinine (mg/dL), median (IQR)

110 (82–152)

110 (82–151)

124 (97–188)

.305

 Hemoglobin (g/L), median (IQR)

120 (108–134)

120 (109–134)

114.5 (104–136)

.538

 MCV (fL/red), median (IQR)

89.5 (86–93.5)

89.5 (86–94)

87.6 (82.4–92.5)

.139

Hypertension

769 (65.0)

513 (71.0)

256 (55.5)

 < .001***

IHD

660 (56.0)

406 (56.2)

254 (55.1)

.764

AF

549 (46.4)

342 (47.3)

207 (45.0)

.437

Hyperlipidemia

578 (49.0)

350 (48.4)

228 (49.5)

.766

Diabetes

489 (41.3)

328 (45.4)

161 (35.0)

 < .001***

Gastroesophageal reflux disease

270 (23.0)

187 (26.0)

83 (18.0)

.002**

Osteoarthritis

231 (19.5)

175 (24.2)

56 (12.1)

 < .001***

CRF

359 (30.3)

223 (31.0)

136 (29.5)

.650

COPD

270 (23.0)

199 (27.5)

71 (15.4)

 < .001***

Anemia

226 (19.1)

163 (22.5)

63 (14.0)

 < .001***

Depression/Anxiety

198 (17.0)

139 (19.2)

59 (13.0)

.004**

Osteoporosis

142 (12.0)

117 (16.2)

25 (5.4)

 < .001***

Any cardiovascular accident

197 (17.0)

140 (19.4)

57 (12.4)

.002**

All ophthalmological conditions

124 (10.5)

87 (12.0)

37 (8.0)

.032*

Peripheral vascular disease

160 (13.5)

114 (16.0)

46 (10.0)

.005**

Any solid cancer

176 (15.0)

109 (15.1)

67 (14.5)

.867

Gout

188 (16.0)

125 (17.3)

63 (14.0)

.103

Asthma

108 (9.1)

80 (11.1)

28 (6.1)

.004**

Hypo/Hyperthyroidism

144 (12.2)

102 (14.1)

42 (9.1)

.011*

Thromboembolism

87 (7.3)

65 (9.0)

22 (5.0)

.006 **

Cognitive impairment

87 (7.3)

78 (11.0)

9 (2.0)

 < .001***

Proportion of patients with

 ≥ 3 comorbidities

1035 (87.4)

665 (92.0)

370 (80.3)

 < .001***

 ≥ 4 comorbidities

895 (76.0)

593 (82.0)

302 (65.5)

 < .001***