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Table 3 Left ventricular dysfunction and structural cardiac abnormality progression

From: Investigation of association of genetic variant rs3918242 of matrix metalloproteinase-9 with hypertension, myocardial infarction and progression of ventricular dysfunction in Irish Caucasian patients with diabetes: a report from the STOP-HF follow-up programme

LVD progression

All (n = 498)

CC (n = 358)

CT/TT (n = 140)

OR

P

LVDD progression, n (%)

111 (22.3)

82 (22.9)

29 (20.7)

1.24 [0.77, 1.99]

ns

LVSD progression, n (%)

19 (3.8)

9 (2.5)

10 (7.1)

2.98 [1.19, 7.51]

0.015

Any LVD progression, n (%)

127 (25.5)

89 (24.9)

38 (27.1)

1.13 [0.72, 1.75]

ns

LAVI progression

41 (8.2)

24 (6.7)

17 (12.1)

1.92 [1.0, 3.70]

0.047

LVH progression, n (%)

33 (6.6)

24 (6.7)

9 (6.4)

0.96 [0.43, 2.11]

ns

Any LVD or SCA progression, n (%)

166 (33.3)

114 (31.8)

52 (37.1)

1.40 [0.91, 2.14]

ns

  1. LVD left ventricular dysfunction, LVDD left ventricular diastolic dysfunction, LVSD left ventricular systolic dysfunction, LVH left ventricular hypertrophy, LAVI left atrial volume index, SCA structural cardiac abnormality