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Table 1 Patient baseline demographics and medical history

From: Investigation of association of genetic variant rs3918242 of matrix metalloproteinase-9 with hypertension, myocardial infarction and progression of ventricular dysfunction in Irish Caucasian patients with diabetes: a report from the STOP-HF follow-up programme

 

All (n = 498)

CC (n = 358)

CT/TT (n = 140)

P

Demographics

 Age, years, median [IQR]

66.2 [58.2:72.9]

66.0 [57.8:73.0]

67.3 [59.6:72.9]

ns

 Male N (%)

297 (59.6%)

207 (57.8%)

90 (64.3%)

ns

 BMI, median [IQR]

29 [26:33]

29 [26:33]

29 [26:33]

ns

 SBP, median [IQR]

133 [122:149]

130 [119:142]

133 [122:149]

ns

 DBP, median [IQR]

80 [72:86]

79 [72:86]

80 [73:87]

ns

 Heart rate, median [IQR]

72 [63:80]

72 [63:81]

71 [64:80]

ns

Medical history

 Hypertension, n (%)

364 (73.1%)

263 (73.5%)

101 (72.1%)

ns

 Myocardial infarction, n (%)

55 (11.0%)

30 (8.4%)

25 (17.9%)

0.002

 Angina, IHD, n (%)

39 (7.89%)

27 (7.5%)

12 (8.6%)

ns

 Hypercholesterolaemia, n (%)

381 (76.5%)

272 (76.0%)

109 (77.9%)

ns

 Arrhythmia, n (%)

35 (7.0%)

28 (7.8%)

7 (5.0%)

ns

 Atrial fibrillation, n (%)

38 (7.6%)

29 (8.1%)

9 (6.4%)

ns

 Stroke/TIA, n (%)

33 (6.6%)

25 (7.0%)

8 (5.7%)

ns

 Valvular heart disease, n (%)

6 (1.2%)

5 (81.4%)

1 (0.7%)

ns

Blood biochemistry

 BNP, median [IQR]

19.7 [7.8:54.6]

19.1 [7.8:51.1]

23.3 [7.9:57.6]

ns

 Cholesterol, median [IQR]

4.1 [3.6:4.7]

4.1 [3.6:4.7]

4.1 [3.4:4.7]

ns

 LDL, median [IQR]

2.1 [1.7:2.6]

2.1 [1.6:2.6]

2.0 [1.7:2.6]

ns

 HDL, median [IQR]

1.1 [0.9:1.4]

1.1 [0.9:1.4]

1.1 [0.8:1.4]

ns

 Triglycerides, median [IQR]

1.7 [1.1:2.4]

1.7 [1.1:2.4]

1.6 [1.2:2.5]

ns

 Glucose, median [IQR]

8.2 [6.3:11.1]

8.2 [6.3:10.9]

8.7 [6.5:11.3]

ns

 Creatinine, median [IQR]

87 [72:105]

89 [72:105]

82 [73:102]

ns

  1. IQR interquartile range, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, IHD ischemic heart disease, TIA transient ischaemic attack, BNP B-type natriuretic peptide, LDL low density lipoprotein cholesterol, HDL high density lipoprotein cholesterol