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Table 1 Baseline clinical characteristics of the study population

From: Differing effects of beta-blockers on long-term clinical outcomes following percutaneous coronary intervention between patients with mid-range and reduced left ventricular ejection fraction

 

mrEF

rEF

β-blocker ( +) (n = 163)

β-blocker ( −) (n = 153)

p value

β-blocker ( +) (n = 99)

β-blocker ( −) (n = 102)

p value

Age (years)

64.9 ± 12.1

65.7 ± 10.8

0.567

66.6 ± 10.6

67.8 ± 11.3

0.435

Men (%)

137 (84.1)

125 (81.7)

0.579

84 (84.9)

88 (86.3)

0.774

BMI, (kg/m2)

24.1 ± 4.0

23.1 ± 3.5

0.015

24.2 ± 4.0

23.2 ± 4.0

0.082

Hypertension, n (%)

114 (69.9)

96 (62.8)

0.176

76 (76.8)

60 (58.8)

0.007

Diabetes mellitus, n (%)

76 (46.6)

69 (45.1)

0.785

53 (53.5)

51 (50.0)

0.616

CKD, n (%)

58 (36.5)

51 (33.6)

0.589

42 (43.3)

50 (51.0)

0.280

eGFR, (mL/min/1.73 m2)

68.7 ± 27.7

66.6 ± 24.9

0.489

63.6 ± 24.6

60.0 ± 38.5

0.427

Family history of IHD, n (%)

47 (29.2)

36 (23.5)

0.255

28 (28.6)

21 (20.6)

0.189

Current smoking, n (%)

43 (26.4)

41 (26.8)

0.933

21 (21.2)

20 (19.6)

0.778

Hemoglobin, g/dL

14.5 ± 1.3

13.2 ± 2.1

0.319

13.2 ± 1.8

12.6 ± 2.1

0.131

LDL-C, mg/dL

111.1 ± 32.3

115.2 ± 31.5

0.249

114.9 ± 38.1

115.0 ± 37.8

0.983

HDL-C, mg/dL

44.8 ± 14.3

44.7 ± 14.6

0.983

41.2 ± 10.7

41.5 ± 12.8

0.867

Triglycerides, mg/dL

131.3 ± 71.6

121.9 ± 74.1

0.251

117.8 ± 58.3

117.5 ± 65.8

0.974

Systolic BP, mmHg

135.6 ± 25.6

132.7 ± 21.9

0.289

124.7 ± 23.1

120.1 ± 21.0

0.143

Diastolic BP, mmHg

74.6 ± 15.3

73.2 ± 13.9

0.401

72.2 ± 13.1

65.8 ± 11.9

 < 0.001

LVEF, %

44.5 ± 3.1

44.5 ± 2.9

0.972

30.6 ± 6.8

30.3 ± 7.4

0.755

Multivessel disease, n (%)

99 (61.9)

92 (60.1)

0.752

66 (66.7)

79 (77.5)

0.088

LMT lesion, n (%)

2 (1.2)

7 (4.6)

0.074

6 (6.1)

2 (2.0)

0.137

LAD lesion, n (%)

86 (52.8)

72 (47.1)

0.311

47 (47.5)

52 (51.0)

0.619

MLD at baseline, (mm)

0.3 (0.3–0.4)

0.4 (0.3–0.5)

0.184

0.3 (0.2–0.4)

0.4 (0.3–0.5)

0.036

MLD post-procedure, (mm)

2.7 (2.6–2.8)

2.7 (2.6–2.8)

0.708

2.7 (2.6–2.8)

2.5 (2.3–2.7)

0.062

Reference lumen diameter, (mm)

2.9 (2.8–3.0)

3.0 (2.9–3.1)

0.053

2.9 (2.8–3.0)

3.0 (2.8–3.1)

0.379

Type B2/ C lesion, n (%)

121 (74.2)

102 (66.7.0)

0.140

80 (80.8)

58 (56.9)

 < 0.001

Stent size, (mm)

3.0 (3.0–3.25)

3.0 (3.0–3.25)

0.579

3.0 (2.75–3.0)

3.0 (2.75–3.0)

0.780

BMS

86 (52.8)

72 (47.1)

0.311

40 (40.4)

46 (45.1)

0.569

DES

48 (29.5)

46 (30.1)

0.905

37 (37.4)

18 (17.7)

0.003

ACS, n (%)

75 (46.0)

67 (43.8)

0.692

42 (42.4)

47 (46.1)

0.602

Medications

 

 Aspirin, n (%)

153 (93.9)

139 (90.9)

0.312

97 (98.0)

79 (77.5)

 < 0.001

 Ca-blockers, n (%)

36 (22.1)

34 (22.2)

0.977

19 (19.2)

19 (18.6)

0.919

 ACE-Is/ARBs, n (%)

117 (71.8)

104 (68.0)

0.556

70 (70.7)

55 (53.9)

0.014

 Statins, n (%)

101 (62.0)

73 (47.7)

0.011

62 (62.6)

36 (35.3)

 < 0.001

  1. Data is presented as n (%), mean ± standard deviation, or median (interquartile range)
  2. ACEI angiotensin-converting enzyme inhibitors, ACS acute coronary syndrome, ARB angiotensin receptor blockers, BMI body mass index, BP blood pressure, BMS bare metal stent, CKD chronic kidney disease, DES drug-eluting stent, eGFR estimated glomerular filtration rate, HDL-C high-density lipoprotein cholesterol, IHD ischemic heart disease, LAD left anterior descending artery, LDL-C low-density lipoprotein cholesterol, LMT left main trunk, LVEF left ventricular ejection fraction, MLD minimal lumen diameter, mrEF mid-range ejection fraction