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Table 3 Predictors for 1-year all-cause death

From: Addition of routine blood biomarkers to TIMI risk score improves predictive performance of 1-year mortality in patients with ST-segment elevation myocardial infarction

Variables

Univariate analysis

Multivariate analysis

HR

95% CI

p value

HR

95% CI

p value

Age (per 10-year-old increase)

1.960

1.621–2.370

 < 0.001

1.416

1.097–1.828

0.008

Male

0.610

0.371–1.003

0.051

1.783

0.802–3.962

0.156

Body weight < 67 kg

1.807

1.123–2.907

0.015

1.555

0.735–3.291

0.249

Diabetes mellitus

1.824

1.146–2.903

0.011

1.062

0.496–2.272

0.878

Hypertension

1.655

1.045–2.621

0.032

0.970

0.489–1.923

0.930

Systolic BP < 100 mmHg

4.459

2.770–7.178

 < 0.001

2.568

1.357–4.860

0.004

Heart rate > 100 beats/minute

3.022

1.796–5.085

 < 0.001

1.239

0.548–2.802

0.606

Killip class II–IV

5.445

3.455–8.581

 < 0.001

2.426

1.367–4.303

0.002

LVEF < 40%

5.080

2.981–8.658

 < 0.001

1.889

1.008–3.541

0.047

Anterior wall infarction

2.061

1.261–3.366

0.004

2.084

1.056–4.114

0.034

Multivessel disease

1.526

0.928–2.509

0.095

1.047

0.511–2.144

0.900

Post-TIMI flow < 3

3.782

2.371–6.032

 < 0.001

1.843

1.006–3.379

0.048

Hypoxic liver injury*

3.631

2.308–5.710

 < 0.001

2.019

1.104–3.695

0.023

Dysglycemia†

5.008

3.173–7.904

 < 0.001

2.535

1.324–4.855

0.005

Anemia

3.702

2.338–5.863

 < 0.001

2.071

1.093–3.923

0.026

NLR > 4.3

3.796

2.336–6.166

 < 0.001

3.651

1.927–6.918

 < 0.001

Estimated GFR < 60 mL/min/1.73 m2

3.879

2.454–6.131

 < 0.001

0.791

0.364–1.720

0.554

Peak CK-MB (log)

1.637

0.951–2.821

0.075

1.228

0.618–2.441

0.558

Symptom to balloon time > 4 h

2.094

1.316–3.333

0.002

1.477

0.731–2.988

0.277

  1. HR hazard ratio, CI confidence interval, BP blood pressure, LVEF left ventricular ejection fraction, NLR neutrophil to lymphocyte ratio, GFR glomerular filtration rate, CK-MB creatine kinase-myocardial band isoenzyme, ALP alkaline phosphatase
  2. *Hypoxic liver injury was defined as an elevation of serum transaminase level more than twice the upper limit of normal
  3. †Dysglycemia was defined as serum glucose < 90 or > 250 mg/dL
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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