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Table 3 GMDR analysis on the best SNP-SNP and gene-diabetes interaction models

From: BRD4 and PIN1 gene polymorphisms are associated with high pulse pressure risk in a southeastern Chinese population

Locus no Best combination Cross-validation consistency Testing accuracy P values
SNP-SNP interactionsa     
2 rs2233682, rs4808278 8/10 0.5093 0.1719
3 rs2233678, rs2233682, rs4808278 7/10 0.4991 0.1719
Gene-diabetes interactionsb     
2 rs4808278, diabetes 10/10 0.5783 0.0107
3 rs2233678, rs4808278, diabetes 9/10 0.5747 0.0107
  1. GMDR generalized multifactor dimensionality reduction, SNP single nucleotide polymorphism, BMI body mass index
  2. aAdjusted for age, sex, smoking, drinking, BMI and diabetes
  3. bAdjusted for age, sex, smoking, drinking and BMI