BRD4 and PIN1 gene polymorphisms are associated with high pulse pressure risk in a southeastern Chinese population

Table 3 GMDR analysis on the best SNP-SNP and gene-diabetes interaction models

Locus no	Best combination	Cross-validation consistency	Testing accuracy	P values
SNP-SNP interactions^a
2	rs2233682, rs4808278	8/10	0.5093	0.1719
3	rs2233678, rs2233682, rs4808278	7/10	0.4991	0.1719
Gene-diabetes interactions^b
2	rs4808278, diabetes	10/10	0.5783	0.0107
3	rs2233678, rs4808278, diabetes	9/10	0.5747	0.0107

GMDR generalized multifactor dimensionality reduction, SNP single nucleotide polymorphism, BMI body mass index
^aAdjusted for age, sex, smoking, drinking, BMI and diabetes
^bAdjusted for age, sex, smoking, drinking and BMI

ISSN: 1471-2261