Table 2 Genotype and allele frequencies of four single nucleotide polymorphisms in the BRD4 and PIN1 genes in normal and high pulse pressure groups
SNPs | Genotypes and alleles | Frequencies N (%) | P value | |
|---|---|---|---|---|
Case (n = 460) | Control (n = 438) | |||
AA | 250 (0.543) | 240 (0.548) | 0.046878 | |
BRD4 | AT | 164 (0.357) | 173 (0.395) | |
rs4808278 | TT | 46 (0.100) | 25 (0.057) | |
Allele, T (%) | 256 (0.278) | 223 (0.255) | 0.256363 | |
GG | 443 (0.963) | 418 (0.954) | 0.511810 | |
PIN1 | CG | 17 (0.037) | 20 (0.046) | |
rs2233678 | CC | 0 (0) | 0 (0) | |
Allele, C (%) | 17 (0.018) | 20 (0.023) | 0.516271 | |
GG | 438 (0.952) | 422 (0.963) | 0.400651 | |
PIN1 | AG | 22 (0.048) | 16 (0.037) | |
rs2233682 | AA | 0 (0) | 0 (0) | |
Allele, A(%) | 22 (0.024) | 16 (0.018) | 0.405751 | |
CC | 225 (0.489) | 232 (0.530) | 0.476216 | |
PIN1 | CT | 184 (0.400) | 162 (0.370) | |
rs2287838 | TT | 51 (0.111) | 44 (0.100) | |
Allele, T (%) | 286 (0.311) | 250 (0.285) | 0.238116 | |