Skip to main content

Table 2 Genotype and allele frequencies of four single nucleotide polymorphisms in the BRD4 and PIN1 genes in normal and high pulse pressure groups

From: BRD4 and PIN1 gene polymorphisms are associated with high pulse pressure risk in a southeastern Chinese population

SNPs Genotypes and alleles Frequencies N (%) P value
Case (n = 460) Control (n = 438)
  AA 250 (0.543) 240 (0.548) 0.046878
BRD4 AT 164 (0.357) 173 (0.395)
rs4808278 TT 46 (0.100) 25 (0.057)
  Allele, T (%) 256 (0.278) 223 (0.255) 0.256363
  GG 443 (0.963) 418 (0.954) 0.511810
PIN1 CG 17 (0.037) 20 (0.046)
rs2233678 CC 0 (0) 0 (0)
  Allele, C (%) 17 (0.018) 20 (0.023) 0.516271
  GG 438 (0.952) 422 (0.963) 0.400651
PIN1 AG 22 (0.048) 16 (0.037)
rs2233682 AA 0 (0) 0 (0)
  Allele, A(%) 22 (0.024) 16 (0.018) 0.405751
  CC 225 (0.489) 232 (0.530) 0.476216
PIN1 CT 184 (0.400) 162 (0.370)
rs2287838 TT 51 (0.111) 44 (0.100)
  Allele, T (%) 286 (0.311) 250 (0.285) 0.238116
  1. A chi-squared test was used to calculate the P values