Fig. 4

ROC curve for diagnosis of AMI divided by age, gender and renal function. a Male patients younger than 60 years with eGFR ≥ 60 mL min⁻¹ (1.73 m²)⁻¹, Cut-off = 0.24 ng mL⁻¹ with 91.6% sensitivity and 100.0% specificity. AUC = 0.984 [95% CI (0.973, 0.991)]. b Male patients aged 60 or above with eGFR ≥ 60 mL min⁻¹ (1.73 m²)⁻¹, Cut-off = 0.31 ng mL⁻¹ with 90.9% sensitivity and 100.0% specificity. AUC = 0.962 [95% CI (0.949, 0.973)]. c Female patients younger than 60 years with eGFR ≥ 60 mL min⁻¹ (1.73 m²)⁻¹, Cut-off = 0.27 ng mL⁻¹ with 93.2% sensitivity and 100.0% specificity. AUC = 0.979 [95% CI (0.941, 0.995)]. d Female patients aged 60 or above with eGFR ≥ 60 mL min⁻¹ (1.73 m²)⁻¹, Cut-off = 0.27 ng mL⁻¹ with 91.0% sensitivity and 100.0% specificity. AUC = 0.946 [95% CI (0.918, 0.966)]. e Male patients younger than 60 years with 30 ≤ eGFR < 60 mL min⁻¹·(1.73 m²)⁻¹, Cut-off = 0.72 ng mL⁻¹ with 81.4% sensitivity and 100.0% specificity. AUC = 0.869 [95% CI (0.772, 0.936)]. f Male patients aged 60 or above with 30 ≤ eGFR < 60 mL min⁻¹·(1.73 m²)⁻¹, Cut-off = 0.50 ng mL⁻¹ with 89.5% sensitivity and 100.0% specificity. AUC = 0.959 [95% CI (0.932, 0.978)]. g Female patients aged 60 or above with 30 ≤ eGFR < 60 mL min⁻¹·(1.73 m²)⁻¹, Cut-off = 0.59 ng mL⁻¹ with 91.4% sensitivity and 100.0% specificity. AUC = 0.952 [95% CI (0.910, 0.979)]. h Male patients aged 60 or above with 15 ≤ eGFR < 30 mL min⁻¹ (1.73 m²)⁻¹, Cut-off = 2.61 ng mL⁻¹ with 80.4% sensitivity and 92.1% specificity. AUC = 0.907 [95% CI (0.827, 0.958)]. i Female Patients aged 60 or above with 15 ≤ eGFR < 30 mL min⁻¹ (1.73 m²)⁻¹, Cut-off = 1.90 ng mL⁻¹ with 89.3% sensitivity and 92.1% specificity. AUC = 0.943 [95% CI (0.846, 0.987)]. AMI acute myocardial infarction, hs-cTnI high-sensitive cardiac troponin I, AUC area under the curve, ROC receiver-operating characteristic, eGFR estimated glomerular filtration rate