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Table 2 Unadjusted and adjusted hazard ratios and 95% confidence intervals for cardiovascular mortality according to the tertitles of leukocyte and its subtypes

From: Differential leukocyte counts and cardiovascular mortality in very old patients with acute myocardial infarction: a Chinese cohort study

Variables

Tertile 1

Tertile 2

Tertile 3

P value

Leukocytes

Unadjusted

1.00

1.02 (0.67–1.55)

1.72 (1.16–2.53)

0.005

Adjusteda

1.00

0.79 (0.47–1.31)

1.14 (0.66–1.96)

0.288

Neutrophils

Unadjusted

1.00

1.93 (1.24–3.00)

2.86(1.87–4.38)

< 0.001

Adjusteda

1.00

2.02 (1.15–3.53)

2.53(1.40–4.55)

0.008

Lymphocytes

Unadjusted

1.00

0.53 (0.37–0.77)

0.38(0.26–0.57)

< 0.001

Adjusteda

1.00

0.51(0.33–0.81)

0.47(0.28–0.77)

0.002

Monocytes

Unadjusted

1.00

1.19(0.78–1.80)

1.49(1.00–2.23)

0.132

Adjusteda

1.00

1.15(0.70–1.88)

0.97(0.58–1.63)

0.769

Eosinophils

Unadjusted

1.00

0.40(0.27–0.58)

0.42(0.29–0.63)

< 0.001

Adjusteda

1.00

0.46(0.29–0.73)

0.46(0.28–0.76)

0.001

Basophils

Unadjusted

1.00

0.36(0.23–0.55)

0.31(0.18–0.55)

< 0.001

Adjusteda

1.00

0.37(0.21–0.66)

0.28(0.13–0.61)

0.001

NMLR

Unadjusted

1.00

1.78 (1.11–2.84)

4.05 (2.64–6.22)

< 0.001

Adjusteda

1.00

1.31 (0.75–2.31)

3.21(1.75–5.35)

< 0.001

NLR

Unadjusted

1.00

1.81(1.14–2.87)

3.74(2.44–5.71)

< 0.001

Adjusteda

1.00

1.33(0.76–2.34)

2.79(1.59–4.88)

< 0.001

MLR

Unadjusted

1.00

1.53(0.96–2.44)

3.30(2.17–5.02)

< 0.001

Adjusteda

1.00

1.41(0.82–2.44)

2.11(1.22–3.67)

0.024

ELR

Unadjusted

1.00

0.41(0.28–0.60)

0.40(0.27–0.59)

< 0.001

Adjusteda

1.00

0.38 (0.23–0.61)

0.46(0.28–0.75)

< 0.001

  1. aAdjusted for age, male gender, BMI, Family history of CAD, smoking, hypertension, DM, HDL-C, non-HDL-C, hsCRP, Creatinine, LVEF, Troponin I, use of statin, ACE-I/ARB, PCI
  2. BMI body mass index, CAD coronary artery disease, DM diabetes mellitus, HDL-C high-density lipoprotein cholesterol, PCI percutaneous coronary intervention, hsCRP high sensitivity C-reactive protein, NMLR neutrophil-plus-monocyte-to-lymphocyte ratio, NLR neutrophil-to-lymphocyte ratio, MLR monocyte-to-lymphocyte ratio, ELR eosinophil-to-leukocyte ratio, ACE-I agiotensin-converting enzyme inhibitors, ARB angiotensin receptor blockers